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The primary patency of drug-eluting balloon versus conventional balloon angioplasty in hemodialysis patients with arteriovenous fistula stenoses

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Abstract

Objective

The aim of this article is to assess and compare the rate of primary patency achieved by drug-eluting balloon angioplasty (DEBA) and conventional balloon angioplasty (CBA) in hemodialysis arteriovenous fistula stenoses.

Methods

This retrospective study consists of 52 patients with significant arteriovenous fistulas stenoses who were treated with DEBA (n = 26) or CBA (n = 26) between January 2013 and January 2015. Only those patients with postprocedural technical and clinical success of 100 % were selected from the database. Primary patency rates of fistulas at 6 and 12 months were evaluated with Doppler ultrasonography as well as clinically. The Kaplan-Meier method was used to compare the primary assisted patency rates for the two groups.

Results

The type of AVFs were 41 (78.8 %) radiocephalic and 11 (21.2 %) brachiocephalic. Primary patency rates between the DEBA and CBA group had a statistically significant difference at 12 months (p < 0.05). However there was no statistically significant difference at the 6-month follow-up period (p = 0.449). There was no statistically significant difference among the patient age, patient gender and fistula type of the two groups (p > 0.05).

Conclusion

Drug-eluting balloon angioplasty proved to be an effective treatment of hemodialysis AVFs stenosis, with a high primary patency rate at 12 months.

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References

  1. Gilmore J. KDOQI clinical practice guidelines and clinical practice recommendations-2006 updates. Nephrol Nurs J. 2006;33:487–8.

    PubMed  Google Scholar 

  2. Stone GW, Moses JW, Ellis SG, et al. Safety and efficacy of sirolismus and paclitaxel-eluting coronary stents. N Engl J Med. 2007;356(10):998–1008.

    Article  CAS  PubMed  Google Scholar 

  3. Scheller B, Clever YP, Kelsch B, Hehrlein C, Bocksch W, Rutsch W, et al. Long term follow up after treatment of coronary in-stent restenosis with a paclitaxel-coated balloon catheter. JACC Cardiovasc Interv. 2012;5(3):323–30.

    Article  PubMed  Google Scholar 

  4. Tepe G, Zeller T, Albbrecht T, et al. Local delivery of paclitaxel to inhibit restenosis during angioplasty of the leg. N Engl J Med. 2008;358:689–99.

    Article  CAS  PubMed  Google Scholar 

  5. Werk M, Langner S, Reinkensmeier B, et al. Inhibition of restenosis in femoropopliteal arteries: paclitaxel-coated versus uncoated balloon: femoral paclitaxel randomized pilot trial. Circulation. 2008;118:1358–65.

    Article  CAS  PubMed  Google Scholar 

  6. Kitrou P, Spiliopoulos S, Katsanos K, Papachristou E, Siablis Karnabatidis D. Paclitaxel-coated balloon angioplasty versus plain balloon angioplasty for dysfunctional arteriovenous fistulae: 1-year results of a prospective randomized controlled trial. J Vasc Interv Radiol. 2015;26:348–54.

    Article  PubMed  Google Scholar 

  7. Patanè D, Giuffrida S, Morale W, et al. Drug-eluting balloon for the treatment of failing hemodialytic radiocephalic arteriovenous fistulas: our experience in the treatment of juxta-anastomotic stenoses. J Vasc Access. 2014;15(5):338–43.

    Article  PubMed  Google Scholar 

  8. Campos RP, Do Nascimento MM, Chula DC, Do Nascimento DE, Riella MC. Stenosis in hemodialysis arteriovenous fistula: evaluation and treatment. Hemodial Int. 2006;10:152–61.

    Article  PubMed  Google Scholar 

  9. Roy-Chaudhury P, Kelly BS, Miller MA, et al. Venous neointimal hyperplasia in polytetrafluoroethylene dialysis grafts. Kidney Int. 2001;59:2325–34.

    Article  CAS  PubMed  Google Scholar 

  10. Davidson CJ, Newman GE, Sheikh KH, Kisslo K, Stack RS, Schwab SJ. Mechanisms of angioplasty in haemodialysis fistula stenoses evaluated by intravascular ultrasound. Kidney Int. 1991;40:91–5.

    Article  CAS  PubMed  Google Scholar 

  11. Axel DI, Kunert W, Goeggelmann C, et al. Paclitaxel inhibits arterial smooth muscle cell proliferation and migration in vitro and in vivo using local drug delivery. Circulation. 1997;96:636–45.

    Article  CAS  PubMed  Google Scholar 

  12. Scheller B, Speck U, Abramjuk C, et al. Paclitaxel balloon coating, anovel method for prevention and therapy of restenosis. Circulation. 2004;110:810–4.

    Article  CAS  PubMed  Google Scholar 

  13. Unverdorben M, Vallbracht C, Cremers B, et al. Paclitaxel-coated balloon catheter versus paclitaxel-coated stent for the treatment of coronary in-stent restenosis. Circulation. 2009;119:2986–94.

    Article  CAS  PubMed  Google Scholar 

  14. Manninen HI, Kaukanen ET, Ikaheimo R, et al. Brachial Arterial Access: endovascular treatment of failing Brescia–Cimino hemodialysis fistulas: initial success and long-term results. Radiology. 2001;218:711–8.

    Article  CAS  PubMed  Google Scholar 

  15. Miquelin DG, Reis LF, da Silva AA, de Godoy JM. Percutaneous transluminal angioplasty in the treatment of stenosis of arteriovenous fistulae for hemodialysis. Int Arch Med. 2008;23:16.

    Article  Google Scholar 

  16. Kim WS, Pyun WB, Kang BC. The primary patency of percutaneous transluminal angioplasty in hemodialysis patients with vascular access failure. Korean Circ J. 2011;41(9):512–7.

    Article  PubMed  PubMed Central  Google Scholar 

  17. Mantha M, Killen JP, Baer R, Moffat J. Percutaneous maintenance and salvage of dysfunctional arteriovenous fistulae and grafts by nephrologists in Australia. Nephrology (Carlton). 2011;16(1):46–52.

    Article  Google Scholar 

  18. Mortamais J, Papillard M, Girouin N, et al. Endovascular treatment of juxta-anastomotic venous stenoses of forearm radiocephalic fistulas: long-term results and prognostic factors. J Vasc Interv Radiol. 2013;24(4):558–64.

    Article  PubMed  Google Scholar 

  19. Lee T, Roy-Chaudhury P. Advances and new frontiers in the pathophysiology of venous neointimal hyperplasia and dialysis access stenosis. Adv Chron Kidney Dis. 2009;16(5):329–33.

    Article  Google Scholar 

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Correspondence to Mehmet Burak Çildağ.

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Çildağ, M.B., Köseoğlu, Ö.F.K., Akdam, H. et al. The primary patency of drug-eluting balloon versus conventional balloon angioplasty in hemodialysis patients with arteriovenous fistula stenoses. Jpn J Radiol 34, 700–704 (2016). https://doi.org/10.1007/s11604-016-0577-8

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  • DOI: https://doi.org/10.1007/s11604-016-0577-8

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