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A case of tubulocystic carcinoma of the kidney with aggressive features

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Abstract

Tubulocystic carcinoma of the kidney is rare and typically indolent. Our case involved an aggressive tubulocystic carcinoma as well as the radiological confirmation of its relation to papillary renal cell carcinoma. A 46-year-old male presented with renal multiloculated cysts with a solid part. On computed tomography and magnetic resonance imaging, the solid part showed the characteristics of papillary renal cell carcinoma. Contrast enhancement of the solid part was fluffy and sparse because of the coexistence of cysts. Perirenal fat invasion resulted in exophytic cysts, and renal-hilar cystic lymph node metastasis existed. The histopathological diagnosis was tubulocystic carcinoma associated with areas of papillary renal cell carcinoma and poorly differentiated carcinoma with metastasis. Our case suggests that the solid part enhancement of tubulocystic carcinoma tends to be fluffy and sparse, and exophytic cysts and cystic lymph nodes may show radiologically aggressive findings.

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Abbreviations

TCK:

Tubulocystic carcinoma of the kidney

CT:

Computed tomography

MRI:

Magnetic resonance imaging

pRCC:

Papillary renal cell carcinoma

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Acknowledgments

The authors thank Dr. Toru Higaki (Department of Diagnostic Radiology, Institute of Biomedical and Health Sciences, Hiroshima University) for technical assistant.

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Authors and Affiliations

  1. Department of Diagnostic Radiology, Institute of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 7340037, Japan

    Yoko Maeda, Yukiko Honda, Yuko Nakamura, Makoto Iida & Kazuo Awai

  2. Department of Molecular Pathology, Institute of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 7340037, Japan

    Keisuke Goto, Kazuhiro Sentani & Wataru Yasui

  3. Department of Diagnostic Pathology, Kochi Red Cross Hospital, 2-13-51 Shin-honmachi, Kochi, 7808562, Japan

    Naoto Kuroda

  4. Department of Urology, Institute of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 7340037, Japan

    Keisuke Goto, Tetsutaro Hayashi, Jun Teishima & Akio Matsubara

  5. Molecular Imaging Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 9000 Kville Pike, Building 10, B3B47, Bethesda, MD, 20892, USA

    Yuko Nakamura

  6. Department of Diagnostic Radiology, National Hospital Organization Kure Medical Center, 3-1 Aoyama-cho, Kure, Hiroshima, 7370023, Japan

    Yoko Maeda & Naoyuki Toyota

Authors
  1. Yoko Maeda
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  2. Keisuke Goto
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  3. Yukiko Honda
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  4. Naoto Kuroda
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  5. Kazuhiro Sentani
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  6. Wataru Yasui
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  7. Tetsutaro Hayashi
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  8. Jun Teishima
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  9. Akio Matsubara
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  10. Yuko Nakamura
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  11. Naoyuki Toyota
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  12. Makoto Iida
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  13. Kazuo Awai
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Corresponding author

Correspondence to Yukiko Honda.

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The authors indicated no potential conflicts of interest.

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Cite this article

Maeda, Y., Goto, K., Honda, Y. et al. A case of tubulocystic carcinoma of the kidney with aggressive features. Jpn J Radiol 34, 307–311 (2016). https://doi.org/10.1007/s11604-016-0525-7

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  • DOI: https://doi.org/10.1007/s11604-016-0525-7

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