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Association between reperfusion and shrinkage percentage of the aneurysmal sac after embolization of pulmonary arteriovenous malformation: evaluation based on contrast-enhanced thin-section CT images

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Abstract

Purpose

To investigate an association between reperfusion and the percentage of shrinkage of the aneurysmal sac after embolization of pulmonary arteriovenous malformation (PAVM) and to determine the cutoff value of the shrinkage percentage for indicating reperfusion.

Materials and methods

Twenty-two PAVMs with completely embolized feeding arteries with coils were examined. The percentage of sac shrinkage and the presence of reperfusion were evaluated on computed tomography before and 1, 3, and 12 months after embolization. The percentages of sac shrinkage were compared between the occlusion and reperfusion groups. The receiver-operating characteristic (ROC) curve was generated to determine the diagnostic efficiency of reperfusion of PAVM by using shrinkage percentages.

Results

Reperfusion was seen in 14, 13, and 11 lesions at 1, 3, and 12 months, respectively. The mean percentage of sac shrinkage was significantly different between the two groups at 3 and 12 months. The area under the ROC curve was 0.991 at 3 months and 0.934 at 12 months. All 9 lesions with <60 % sac shrinkage at 12 months showed reperfusion.

Conclusion

The percentage of sac shrinkage was closely associated with reperfusion after embolization of PAVMs at 3 and 12 months. A shrinkage percentage of <60 % at 12 months indicated reperfusion.

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Conflict of interest

The authors declare no conflicts of interest or funding sources to disclose.

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Authors and Affiliations

  1. Department of Radiology, Okayama University Medical School, 2-5-1 Kitaku Shikatacho, Okayama, 700-8558, Japan

    Satoko Makimoto, Takao Hiraki, Hideo Gobara, Hiroyasu Fujiwara, Toshihiro Iguchi, Yusuke Matsui & Susumu Kanazawa

  2. Department of Diagnostic Radiology 2, Kawasaki Hospital, Kawasaki Medical School, Okayama, Japan

    Hidefumi Mimura

Authors
  1. Satoko Makimoto
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  2. Takao Hiraki
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  3. Hideo Gobara
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  4. Hiroyasu Fujiwara
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  5. Toshihiro Iguchi
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  6. Yusuke Matsui
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  7. Hidefumi Mimura
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  8. Susumu Kanazawa
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Corresponding author

Correspondence to Satoko Makimoto.

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Makimoto, S., Hiraki, T., Gobara, H. et al. Association between reperfusion and shrinkage percentage of the aneurysmal sac after embolization of pulmonary arteriovenous malformation: evaluation based on contrast-enhanced thin-section CT images. Jpn J Radiol 32, 266–273 (2014). https://doi.org/10.1007/s11604-014-0301-5

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  • DOI: https://doi.org/10.1007/s11604-014-0301-5

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