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Nierenarteriennervenablation bei therapieresistenter Hypertonie

Eine Bestandsaufnahme

Renal artery sympathetic denervation for therapy-resistant hypertension

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  • Leitthema
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Der Nephrologe Aims and scope

Zusammenfassung

Die therapierefraktäre essenzielle arterielle Hypertonie ist in der Bevölkerung häufig. Es stehen neuerdings interventionelle Therapieformen für die therapierefraktäre Hypertonie zur Verfügung, wobei hier besonders die perkutane transarterielle renale Denervierung von Bedeutung ist. Das Verfahren ist technisch leicht durchführbar, vergleichsweise sicher und, sofern derzeit beurteilbar, effektiv in Bezug auf die Blutdrucksenkung, allerdings nur in Kombination mit einer wirksamen antihypertensiven Kombinationstherapie. Weitere Studien sind erforderlich, um die Indikationen, die Wirksamkeit und die Sicherheit endgültig beurteilen zu können.

Abstract

Therapy resistant primary arterial hypertension is common in the population. There are emerging interventional therapy concepts for resistant hypertension. Among these, percutaneous transarterial renal sympathetic denervation is of major importance. The procedure is technically not very difficult, relatively safe and produces substantial reductions in blood pressure, as far as can be so far assessed. However, the procedure is only effective as an adjunct to an efficient combination drug therapy for arterial hypertension. Further studies are warranted in order to definitively evaluate indications, efficacy and safety of the procedure.

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Einhaltung ethischer Richtlinien

Interessenkonflikt. M. Hausberg, K. Kisters und H. Reinecke geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.

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Authors and Affiliations

  1. Medizinische Klinik I, Städtisches Klinikum Karlsruhe, Moltkestr. 90, 76133, Karlsruhe, Deutschland

    M. Hausberg

  2. Medizinische Klinik I, St. Anna Hospital, Herne, Deutschland

    K. Kisters

  3. Abteilung für Angiologie, Department für Kardiologie und Angiologie, Universitätsklinikum Münster, Münster, Deutschland

    H. Reinecke

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  1. M. Hausberg
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  2. K. Kisters
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  3. H. Reinecke
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Correspondence to M. Hausberg.

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Hausberg, M., Kisters, K. & Reinecke, H. Nierenarteriennervenablation bei therapieresistenter Hypertonie. Nephrologe 8, 414–422 (2013). https://doi.org/10.1007/s11560-012-0735-7

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