Abstract
Purpose
The aim of this study was to compare the technical success between left spermatic vein (LSV) scleroembolisation achieved with the injection of sclerosant through a diagnostic catheter and through an occluding balloon (OB), in the treatment of male varicocele.
Materials and methods
From January 2012 to September 2013, we prospectively enrolled 100 patients with left varicocele and an indication for LSV scleroembolisation related to symptoms or spermiogram anomalies; patients were randomised to two groups (we wrote a list of 100 lines assigned casually with A or B and each patient was consecutively allocated to group A or B on the basis of this list). Patients in group A underwent injection of the sclerosing agent through an angiographic diagnostic catheter (free catheter technique) and patients in group B through an OB catheter (OB technique). In cases of incomplete occlusion of the LSV, the procedure was completed with coils. Total occlusion of the LSV at post-treatment phlebography during a Valsalva manoeuvre before any coil embolisation was considered a technical success. The rate of complications was also evaluated. The Fischer’s test was used for statistical analysis.
Results
We evaluated a total of 90 patients because five patients for each group were not included in the statistical analysis owing to technical problems or complications. In group A we had a technical success of 75.6 versus 93.4 % in group B, and the difference was statistically significant (P = 0.003); in particular, we had to complete the embolisation with insertion of coils in 11 cases (24.4 %) in group A, and in three cases in group B (6.6 %). In group A, LSV rupture occurred in four cases (8 %) so the procedure was completed by sclerosant injection through the OB located distally to the lesion. These patients were not considered for evaluation. In another case, a high flow shunt towards the inferior vena cava was detected, so the patient underwent OB injection to stop the flow to the shunt, and was not included for statistical evaluation. In group B, vein rupture with contrast leakage was noted in six cases (12 %); nonetheless, all the procedures were completed because the OB was positioned distally to the vessel tear, obviating any retrograde leakage of sclerosant. In group B, in five cases (10 %), we were unable to advance the OB though the LSV ostium so the procedures were completed with the diagnostic catheter and not considered for statistical evaluation.
Conclusion
On the basis of our data, the embolisation of the LSV obtained by injecting the sclerosant through an OB rather than through a diagnostic catheter seems to be more effective in achieving total vein embolisation, as well as allowing a controlled injection of sclerosant even in cases of vein rupture.
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References
Porst H, Bahren W, Lenz M et al (1984) Percutaneous sclerotherapy of varicoceles—an alternative to conventional surgical methods. Br J Urol 56:73–78
Iaccarino V, Venetucci P (2012) Interventional radiology of male varicocele: current status. Cardiovasc Interv Radiol 35:1263–1280
Barrett J, Wells I, Riordan R et al (2000) Endovascular embolization of varicoceles: resorption of tungsten coils in the spermatic vein. Cardiovasc Interv Radiol 23:457–459
Bechara CF, Weakley SM, Kougias P et al (2009) Percutaneous treatment of varicocele with microcoil embolization: comparison of treatment outcome with laparoscopic varicocelectomy. Vascular 17(Suppl 3):S129–S136
Bittles MA, Hoffer EK (2008) Gonadal vein embolization: treatment of varicocele and pelvic congestion syndrome. Sem Interv Radiol 25:261–270
Paul N, Robertson I, Kessel D (1996) Fibre entanglement whilst using the Jackson detachable coil system: a potential pitfall. Chin J Interv Radiol 11:153–155
Sze DY, Kao JS, Frisoli JK et al (2008) Persistent and recurrent postsurgical varicoceles: venographic anatomy and treatment with N-butyl cyanoacrylate embolization. J Vasc Interv Radiol 19:539–545
Tauber R, Johnsen N (1994) Antegrade scrotal sclerotherapy for the treatment of varicocele: technique and late results. J Urol 151:386–390
Tessari L, Cavezzi A, Frullini A (2001) Preliminary experience with a new sclerosing foam in the treatment of varicose veins. Dermatol Surg 27:58–60
Li L, Zeng XQ, Li YH (2010) Safety and effectiveness of transcatheter foam sclerotherapy for testicular varicocele with a fluoroscopic tracing technique. J Vasc Interv Radiol 21:824–828
Gandini R, Konda D, Reale CA et al (2008) Male varicocele: transcatheter foam sclerotherapy with sodium tetradecyl sulfate—outcome in 244 patients. Radiology 246:612–618
Gazzera C, Rampado O, Savio L et al (2006) Radiological treatment of male varicocele: technical, clinical, seminal and dosimetric aspects. Radiol Med 111:449–458
Pedicini V, Poretti D, Mauri G et al (2010) Management of post-surgical biliary leakage with percutaneous transhepatic biliary drainage (PTBD) and occlusion balloon (OB) in patients without dilatation of the biliary tree: preliminary results. Eur Radiol 20:1061–1068
Cozzaglio L, Cimino M, Mauri G et al (2011) Percutaneous transhepatic biliary drainage and occlusion balloon in the management of duodenal stump fistula. J Gastrointest Surg 15:1977–1981
Saad WE, Kitanosono T, Koizumi J et al (2013) The conventional balloon-occluded retrograde transvenous obliteration procedure: indications, contraindications, and technical applications. Tech Vasc Interv Radiol 16:101–151
Seyferth W, Jecht E, Zeitler E (1981) Percutaneous sclerotherapy of varicocele. Radiology 139:335–340
Sigmund G, Bähren W, Gall H et al (1987) Idiopathic varicoceles: feasibility of percutaneous sclerotherapy. Radiology 164:161–168
Lenz M, Hof N, Kersting-Sommerhoff B et al (1996) Anatomic variants of the spermatic vein: importance for percutaneous sclerotherapy of idiopathic varicocele. Radiology 198:425–431
Wunsch R, Efinger K (2005) The interventional therapy of varicoceles amongst children, adolescents and young men. Eur J Radiol 53:46–56
Wollmann JC (2004) The history of sclerosing foams. Dermatol Surg 30:694–703
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Basile, A., Failla, G., La Vignera, S. et al. Left spermatic vein retrograde sclerosis: comparison between sclerosant agent injection through a diagnostic catheter versus through an occluding balloon catheter. Radiol med 120, 483–488 (2015). https://doi.org/10.1007/s11547-014-0478-9
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DOI: https://doi.org/10.1007/s11547-014-0478-9