Skip to main content
Log in

MDCT distinguishing features of focal aortic projections (FAP) in acute clinical settings

  • EMERGENCY RADIOLOGY
  • Published:
La radiologia medica Aims and scope Submit manuscript

Abstract

Focal aortic projections (FAP) are protrusion images of the contrast medium (focal contour irregularity, breaks in the intimal contour, outward lumen bulging or localized blood-filled outpouching) projecting beyond the aortic lumen in the aortic wall and are commonly seen on multidetector computed tomography (MDCT) scans of the chest and abdomen. FAP include several common and uncommon etiologies, which can be demonstrated both in the native aorta, mainly in acute aortic syndromes, and in the post-surgical aorta or after endovascular therapy. They are also found in some types of post-traumatic injuries and in impending rupture of the aneurysms. The expanding, routine use of millimetric or submillimetric collimation of current state-of-the-art MDCT scanners (16 rows and higher) all the time allows the identification and characterization of these small ulcer-like lesions or irregularities in the entire aorta, as either an incidental or expected finding, and provides detailed three-dimensional pictures of these pathologic findings. In this pictorial review, we illustrate the possible significance of FAP and the discriminating MDCT features that help to distinguish among different types of aortic protrusions and their possible evolution. Awareness of some related and distinctive radiologic features in FAP may improve our understanding of aortic diseases, provide further insight into the pathophysiology and natural history, and guide the appropriate management of these lesions.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11
Fig. 12
Fig. 13
Fig. 14
Fig. 15
Fig. 16
Fig. 17
Fig. 18

Similar content being viewed by others

Abbreviations

FAP:

Focal aortic projections

TEVAR:

Thoracic endovascular aortic repair

EVAR:

Endovascular aortic repair

CM:

Contrast medium

MPR:

Multiplanar reconstruction

MIP:

Maximum intensity projection

VR:

Volume rendering

AD:

Aortic dissection

AAS:

Acute aortic syndrome

IMH:

Intramural hematoma

PAU:

Penetrating atherosclerotic ulcer

ULPs:

Ulcer-like projections

IBP:

Intramural blood pool

BAP:

Branch arteries pseudoaneurysm

AA:

Aortic aneurysm

ILT:

Intraluminal thrombus

PSA:

Pseudoaneurysm

MAI:

Minimal aortic injury

BAI:

Blunt aortic injury

CPB:

Cardiopulmonary bypass

PTFE:

Polytetrafluoroethylene

EL:

Endoleak

References

  1. Hiratzka LF, Bakris GL, Beckman JA et al (2010) ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM (2010) Guidelines for the diagnosis and management of patients with thoracic aortic disease. A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, American Association for Thoracic Surgery, American College of Radiology, American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons, and Society for Vascular Medicine. Circulation 121:e266–e369. doi:10.1161/CIR.0b013e3181d4739e

    Article  PubMed  Google Scholar 

  2. Yoo SM, Lee HY, White CS (2010) MDCT evaluation of acute aortic syndrome. Radiol Clin N Am 48:67–83. doi:10.1016/j.rcl.2009.09.006

    Article  PubMed  Google Scholar 

  3. Stein E, Mueller GC, Sundaram B (2014) Thoracic aorta (multidetector computed tomography and magnetic resonance evaluation). Radiol Clin N Am 52(1):195–217. doi:10.1016/j.rcl.2013.08.002

    Article  PubMed  Google Scholar 

  4. Vilacosta I, San Ramon JA (2001) Acute aortic syndrome. Heart 85:265–268. doi:10.1136/heart.85.4.365

    Article  Google Scholar 

  5. Nienaber CA, Powell JT (2012) Management of acute aortic syndromes. Eur Heart J 33:26–35. doi:10.1093/eurheartj/ehr186

    Article  PubMed  Google Scholar 

  6. Harris KM, Braverman AC, Eagle KA et al (2012) Acute aortic intramural hematoma: an analysis from the international registry of acute aortic dissection. Circulation 126:S91–S96. doi:10.1161/CIRCULATIONAHA.111.084541

    Article  PubMed  Google Scholar 

  7. Kruse MJ, Johnson PT, Fishman EK, Zimmerman SL (2013) Aortic intramural hematoma: review of high-risk imaging features. J Cardiovasc Comput Tomogr 7:267–272. doi:10.1016/j.jcct.2013.04.001

    Article  PubMed  Google Scholar 

  8. Chao CP, Walker TG, Kalva SP (2009) Natural history and ct appearances of aortic intramural hematoma. Radiographics 29:791–804. doi:10.1148/rg.293085122

    Article  PubMed  Google Scholar 

  9. Kitai T, Kaji S, Yamamuro A et al (2011) Detection of intimal defect by 64-row multidetector computed tomography in patients with acute aortic intramural hematoma. Circulation 124:S174–S178. doi:10.1161/CIRCULATIONAHA.111.037416

    Article  PubMed  Google Scholar 

  10. Song JK (2011) Aortic intramural hematoma: aspects of pathogenesis. Herz 36:488–497. doi:10.1007/s00059-011-3501-0

    Article  PubMed  Google Scholar 

  11. Park KH, Lim C, Choi JH et al (2008) Prevalence of aortic intimal defect in surgically treated acute type A intramural hematoma. Ann Thorac Surg 86:1494–1500. doi:10.1016/j.athoracsur.2008.06.061

    Article  PubMed  Google Scholar 

  12. Uchida K, Imoto K, Karube N et al (2013) Intramural haematoma should be referred to as thrombosed-type aortic dissection. Eur J Cardiothorac Surg 44:366–369. doi:10.1093/ejcts/ezt040

    Article  PubMed  Google Scholar 

  13. Hayashi H, Matsuoka Y, Sakamoto I et al (2000) Penetrating atherosclerotic ulcer of the aorta: imaging features and disease concept. Radiographics 20:995–1005. doi:10.2214/AJR.08.2073

    Article  CAS  PubMed  Google Scholar 

  14. Siriapisith T, Wasinrat J, Slisatkorn W (2010) Computed tomography of aortic intramural hematoma and thrombosed dissection. Asian Cardiovasc Thorac Ann 18:456–463. doi:10.1177/0218492310380473

    Article  PubMed  Google Scholar 

  15. Sebastià C, Evangelista A, Quiroga S et al (2012) Predictive value of small ulcers in the evolution of acute type B intramural hematoma. Eur J Radiol 81:1569–1574. doi:10.1016/j.ejrad.2011.04.055

    Article  PubMed  Google Scholar 

  16. Ueda T, Chin A, Petrovitch I, Fleischmann D (2012) A pictorial review of acute aortic syndrome: discriminating and overlapping features as revealed by ECG-gated multidetector-row CT angiography. Insights Imaging 3:561–571. doi:10.1007/s13244-012-0195-7

    Article  PubMed Central  PubMed  Google Scholar 

  17. Souza D, Ledbetter S (2012) Diagnostic errors in the evaluation of nontraumatic aortic emergencies. Semin Ultrasound CT MR 33:318–336. doi:10.1053/j.sult.2012.02.001

    Article  PubMed  Google Scholar 

  18. Knollmann FD, Lacomis JM, Ocak I, Gleason T (2013) The role of aortic wall CT attenuation measurements for the diagnosis of acute aortic syndromes. Eur J Radiol 82:2392–2398. doi:10.1016/j.ejrad.2013.09.007

    Article  PubMed  Google Scholar 

  19. Kitai T, Kaji S, Yamamuro A et al (2010) Impact of new development of ulcer-like projection on clinical outcomes in patients with type B aortic dissection with closed and thrombosed false lumen. Circulation 122:S74–S80. doi:10.1161/CIRCULATIONAHA.109.92751720)

    Article  PubMed  Google Scholar 

  20. Hoey ETD, Wai D, Ganeshan A, Watkin RW (2012) Aortic intramural haematoma: pathogenesis, clinical features and imaging evaluation. Postgrad Med J 88:661–667. doi:10.1136/postgradmedj-2011-130677

    Article  PubMed  Google Scholar 

  21. Sueyoshi E, Matsuoka Y, Imada T et al (2002) New development of an ulcer like projection in aortic intramural hematoma: CT evaluation. Radiology 224:536–541. doi:10.1148/radiol.2242011009

    Article  PubMed  Google Scholar 

  22. Lee YK, Seo JB, Jang YM et al (2007) Acute and chronic complications of aortic intramural hematoma on follow-up computed tomography: incidence and predictor analysis. J Comput Assist Tomogr 31:435–440

    Article  PubMed  Google Scholar 

  23. Bosma MS, Quint LE, Williams DM, Patel HJ, Jiang Q, Myles JD (2009) Ulcer like projections developing in noncommunicating aortic dissections: CT findings and natural history. AJR 193:895–905. doi:10.2214/AJR.08.2073

    Article  PubMed  Google Scholar 

  24. Schlatter T, Auriol J, Marcheix B et al (2011) Type B intramural hematoma of the aorta: evolution and prognostic value of intimal erosion. J Vasc Interv Radiol 22:533–541. doi:10.1016/j.jvir.2010.10-028

    Article  PubMed  Google Scholar 

  25. Rajiah P (2013) CT and MRI in the evaluation of thoracic aortic diseases. Int J Vasc Med 2013:797189. doi:10.1155/2013/797189

    PubMed Central  PubMed  Google Scholar 

  26. Coady MA, Rizzo JA, Hammond GL, Pierce JG, Kopf GS, JA Elefteriades (1998) Penetrating ulcer of the thoracic aorta: what is it? How do we recognize it? How do we manage it? J Vasc Surg 27:1006–1016

    Article  CAS  PubMed  Google Scholar 

  27. Evangelista A, Carro A, Moral S et al (2013) Imaging modalities for the early diagnosis of acute aortic syndrome. Nat Rev Cardiol 10:477–486. doi:10.1038/nrcardio.2013.92

    Article  PubMed  Google Scholar 

  28. D’Ancona G, Amaducci A, Rinaudo A et al (2013) Haemodynamic predictors of a penetrating atherosclerotic ulcer rupture using fluid-structure interaction analysis. Interact CardioVasc Thorac Surg 17(3):576–578. doi:10.1093/icvts/ivt245

    Article  PubMed Central  PubMed  Google Scholar 

  29. Ganaha F, Miller DC, Sugimoto K et al (2002) Prognosis of aortic intramural hematoma with and without penetrating atherosclerotic ulcer. A clinical and radiological analysis. Circulation 106:342–348. doi:10.1161/01.CIR.0000022164.26075.5A

    Article  PubMed  Google Scholar 

  30. Williams DM, Lee DY, Hamilton BH et al (1997) The dissected aorta. Part III. Anatomy and radiologic diagnosis of branch-vessel compromise. Radiology 203:37–44

    Article  CAS  PubMed  Google Scholar 

  31. Willoteaux S, Lions C, Gaxotte V, Negaiwi Z, Beregi JP (2004) Imaging of aortic dissection by helical computed tomography (CT). Eur Radiol 14:1999–2008

    Article  PubMed  Google Scholar 

  32. Wu MT, Wu TH, Lee D (2005) Multislice computed tomography of aortic intramural hematoma with progressive intercostal artery tears: the Chinese ring-sword sign. Circulation 111:e92–e93. doi:10.1161/01.CIR.0000154547.65893.45

    Article  PubMed  Google Scholar 

  33. Williams DM, Cronin P, Dasika N et al (2006) Aortic branch artery pseudoaneurysms accompanying aortic dissection. Part I. Pseudoaneurysm anatomy. J Vasc Interv Radiol 17:765–771

    Article  PubMed  Google Scholar 

  34. Williams DM, Cronin P, Dasika N et al (2006) Aortic branch artery pseudoaneurysms accompanying aortic dissection. Part II. Distinction from penetrating atherosclerotic ulcers. J Vasc Interv Radiol 17:773–781

    Article  PubMed  Google Scholar 

  35. Wu MT, Wang YC, Huang YL et al (2011) Intramural blood pools accompanying aortic intramural hematoma: CT appearance and natural course. Radiology 258:705–713. doi:10.1148/radiol.10101270

    Article  PubMed  Google Scholar 

  36. Valente T, Rossi G, Lassandro F et al (2012) MDCT in diagnosing acute aortic syndromes: reviewing common and less common CT findings. Radiol Med 117:393–409. doi:10.1007/s11547-011-0747-9

    Article  CAS  PubMed  Google Scholar 

  37. Cronin P, Carlos RC, Kazerooni EA et al (2012) Aortic branch artery pseudoaneurysms accompanying aortic dissection. Part III: natural history. J Vasc Interv Radiol 23:859–865. doi:10.1016/j.jvir.2012

    Article  PubMed  Google Scholar 

  38. Ferro C, Rossi UG, Seitun S et al (2013) Aortic branch artery pseudoaneurysms associated with intramural hematoma: when and how to do endovascular embolization. Cardiovasc Intervent Radiol 36:422–432. doi:10.1007/s00270-012-0512-z

    Article  PubMed  Google Scholar 

  39. Seitun S, Rossi UG, Cademartiri F et al (2012) MDCT findings of aortic branch artery pseudoaneurysms associated with type B intramural haematoma. Radiol Med 117:789–803. doi:10.1007/s11547-011-0779-1

    Article  CAS  PubMed  Google Scholar 

  40. Svensson LG, Labib SB, Eisenhauer AC, Butterly JR (1999) Intimal tear without hematoma: an important variant of aortic dissection that can elude current imaging techniques. Circulation 99:1331–1336. doi:10.1161/01.CIR.99.10.1331

    Article  CAS  PubMed  Google Scholar 

  41. Erbel R, Alfonso F, Boileau C et al (2001) Diagnosis and management of aortic dissection. Recommendations of the Task Force on Aortic Dissection, European Society of Cardiology. Eur Heart J 22:1642–1681. doi:10.1053/euhj.2001.2782

    Article  CAS  PubMed  Google Scholar 

  42. Chirillo F, Salvador L, Bacchion F et al (2007) Clinical and anatomical characteristics of subtle-discrete dissection of the ascending aorta. Am J Cardiol 100:1314–1319

    Article  PubMed  Google Scholar 

  43. Labruto F, Blomqvist L, Swedenborg J (2011) Imaging the intraluminal thrombus of abdominal aortic aneurysms: techniques, findings, and clinical implications. J Vasc Interv Radiol 22:1069–1075. doi:10.1016/j.jvir.2011.01.454

    Article  PubMed  Google Scholar 

  44. Rakita D, Newatia A, Hines JJ et al (2007) Spectrum of CT findings in rupture and impending rupture of abdominal aortic aneurysms. Radiographics 27:497–507. doi:10.1148/rg.272065026

    Article  PubMed  Google Scholar 

  45. Macedo TA, Stanson AW, Oderich GS et al (2004) Infected aortic aneurysms: imaging findings. Radiology 231:250–257. doi:10.1148/radiol.2311021700

    Article  PubMed  Google Scholar 

  46. Lee WK, Mossop PJ, Little AF et al (2008) Infected (mycotic) aneurysms: spectrum of imaging appearances and management. Radiographics 28:1853–1868. doi:10.1148/rg.287085054

    Article  PubMed  Google Scholar 

  47. Kuhlman JE, Pozniak MA, Collins J, Knisely BL (1998) Radiographic and CT findings of blunt chest trauma: aortic injuries and looking beyond them. Radiographics 18:1085–1106

    Article  CAS  PubMed  Google Scholar 

  48. Mirvis SE (2006) Thoracic vascular injury. Radiol Clin N Am 44:181–197

    Article  PubMed  Google Scholar 

  49. Alkadhi H, Wildermuth S, Desbiolles L et al (2004) Vascular emergencies of the thorax after blunt and iatrogenic trauma: multi–detector row CT and three-dimensional imaging. Radiographics 24:1239–1255

    Article  PubMed  Google Scholar 

  50. Agarwal PP, Chughtai A, Matzinger FR, Kazerooni EA (2009) Multidetector CT of thoracic aortic aneurysms. Radiographics 29:537–552. doi:10.1148/rg.292075080

    Article  PubMed  Google Scholar 

  51. Gavant ML (1999) Helical CT grading of traumatic aortic injuries. Impact on clinical guidelines for medical and surgical management. Radiol Clin N Am 37:553–574

    Article  CAS  PubMed  Google Scholar 

  52. Neschis DG, Scalea TM, Flinn WR, Griffith BP (2008) Blunt aortic injury. N Engl J Med 359:1708–1716. doi:10.1056/NEJMra0706159

    Article  CAS  PubMed  Google Scholar 

  53. Lamarche Y, Berger FH, Nicolaou S et al (2012) Vancouver simplified grading system with computed tomographic angiography for blunt aortic injury. J Thorac Cardiovasc Surg 144:347–354. doi:10.1016/j.jtcvs.2011.10.011

    Article  PubMed  Google Scholar 

  54. Simeone A, Freitas M, Frankel HL (2006) Management options in blunt aortic injury: a case series and literature review. Am Surg 72:25–30

    PubMed  Google Scholar 

  55. Reddy KN, Matatov T, Doucet LD et al (2013) Grading system modification and management of blunt aortic injury. Chin Med J 126:442–445

    PubMed  Google Scholar 

  56. Steenburg SD, Ravenel JG, Ikonomidis JS et al (2008) Acute traumatic aortic injury: imaging evaluation and management. Radiology 248:748–762. doi:10.1148/radiol.2483071416

    Article  PubMed  Google Scholar 

  57. Gunn MLD, Lehnert BE, Lungren RS et al (2014) Minimal aortic injury of the thoracic aorta: imaging appearances and outcome. Emerg Radiol 21:227–233. doi:10.1007/s10140-013-1187-8

    Article  PubMed  Google Scholar 

  58. Goitein O, Fuhrman CR, Lacomis JM (2005) Incidental finding on MDCT of patent ductus arteriosus: use of CT and MRI to assess clinical importance. Am J Roentgenol 184:1924–1931. doi:10.2214/ajr.184.6.01841924

    Article  Google Scholar 

  59. Hoang JK, Martinez S, Hurwitz LM (2009) MDCT angiography after open thoracic aortic surgery: pearls and pitfalls. Am J Roentgenol 192:W20–W27. doi:10.2214/AJR.08.1364

    Article  Google Scholar 

  60. El-Sherief AH, Wu CC, Schoenhagen P et al (2013) Basics of cardiopulmonary bypass: normal and abnormal postoperative CT appearances. Radiographics 33:63–72. doi:10.1148/rg.331115747

    Article  PubMed  Google Scholar 

  61. Prescott-Focht JA, Martinez-Jimenez S, Hurwitz LM et al (2013) Ascending thoracic aorta: postoperative imaging evaluation. Radiographics 33:73–85. doi:10.1148/rg.331125090

    Article  PubMed  Google Scholar 

  62. Valente T, Rossi G, Rea G et al (2014) Multi-detector CT findings of complications of surgical and endovascular treatment of aortic aneurysms. Radiol Clin N Am 52(5) (in press)

  63. White GH, Yu W, May J et al (1997) Endoleak as a complication of endoluminal grafting of abdominal aortic aneurysms: classification, incidence, diagnosis, and management. J Endovasc Surg 4:152–168

    Article  CAS  PubMed  Google Scholar 

  64. Ueda T, Fleischmann D, Dake MD et al (2010) Incomplete endograft apposition to the aortic arch: bird-beak configuration increases risk of endoleak formation after thoracic endovascular aortic repair. Radiology 255:645–652. doi:10.1148/radiol.10091468

    Article  PubMed  Google Scholar 

  65. Kawajiri H, Oka K, Kanda K, Yaku H (2013) Aneurysm formation at both ends of an endograft associated with maladaptive aortic changes after endovascular aortic repair in a healthy patient. Interact CardioVasc Thorac Surg 17:895–897. doi:10.1093/icvts/ivt336

    Article  PubMed Central  PubMed  Google Scholar 

  66. Chernyak V, Rozenblit AM, Patlas M et al (2006) Type II Endoleak after endoaortic graft implantation: diagnosis with helical CT arteriography. Radiology 240:885–893. doi:10.1148/radiol.2403051013

    Article  PubMed  Google Scholar 

Download references

Conflict of interest

The authors declare that they have no conflict of interest to the publication of this article.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Tullio Valente.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Valente, T., Rossi, G., Lassandro, F. et al. MDCT distinguishing features of focal aortic projections (FAP) in acute clinical settings. Radiol med 120, 50–72 (2015). https://doi.org/10.1007/s11547-014-0459-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11547-014-0459-z

Keywords

Navigation