Abstract
Focal aortic projections (FAP) are protrusion images of the contrast medium (focal contour irregularity, breaks in the intimal contour, outward lumen bulging or localized blood-filled outpouching) projecting beyond the aortic lumen in the aortic wall and are commonly seen on multidetector computed tomography (MDCT) scans of the chest and abdomen. FAP include several common and uncommon etiologies, which can be demonstrated both in the native aorta, mainly in acute aortic syndromes, and in the post-surgical aorta or after endovascular therapy. They are also found in some types of post-traumatic injuries and in impending rupture of the aneurysms. The expanding, routine use of millimetric or submillimetric collimation of current state-of-the-art MDCT scanners (16 rows and higher) all the time allows the identification and characterization of these small ulcer-like lesions or irregularities in the entire aorta, as either an incidental or expected finding, and provides detailed three-dimensional pictures of these pathologic findings. In this pictorial review, we illustrate the possible significance of FAP and the discriminating MDCT features that help to distinguish among different types of aortic protrusions and their possible evolution. Awareness of some related and distinctive radiologic features in FAP may improve our understanding of aortic diseases, provide further insight into the pathophysiology and natural history, and guide the appropriate management of these lesions.
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Abbreviations
- FAP:
-
Focal aortic projections
- TEVAR:
-
Thoracic endovascular aortic repair
- EVAR:
-
Endovascular aortic repair
- CM:
-
Contrast medium
- MPR:
-
Multiplanar reconstruction
- MIP:
-
Maximum intensity projection
- VR:
-
Volume rendering
- AD:
-
Aortic dissection
- AAS:
-
Acute aortic syndrome
- IMH:
-
Intramural hematoma
- PAU:
-
Penetrating atherosclerotic ulcer
- ULPs:
-
Ulcer-like projections
- IBP:
-
Intramural blood pool
- BAP:
-
Branch arteries pseudoaneurysm
- AA:
-
Aortic aneurysm
- ILT:
-
Intraluminal thrombus
- PSA:
-
Pseudoaneurysm
- MAI:
-
Minimal aortic injury
- BAI:
-
Blunt aortic injury
- CPB:
-
Cardiopulmonary bypass
- PTFE:
-
Polytetrafluoroethylene
- EL:
-
Endoleak
References
Hiratzka LF, Bakris GL, Beckman JA et al (2010) ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM (2010) Guidelines for the diagnosis and management of patients with thoracic aortic disease. A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, American Association for Thoracic Surgery, American College of Radiology, American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons, and Society for Vascular Medicine. Circulation 121:e266–e369. doi:10.1161/CIR.0b013e3181d4739e
Yoo SM, Lee HY, White CS (2010) MDCT evaluation of acute aortic syndrome. Radiol Clin N Am 48:67–83. doi:10.1016/j.rcl.2009.09.006
Stein E, Mueller GC, Sundaram B (2014) Thoracic aorta (multidetector computed tomography and magnetic resonance evaluation). Radiol Clin N Am 52(1):195–217. doi:10.1016/j.rcl.2013.08.002
Vilacosta I, San Ramon JA (2001) Acute aortic syndrome. Heart 85:265–268. doi:10.1136/heart.85.4.365
Nienaber CA, Powell JT (2012) Management of acute aortic syndromes. Eur Heart J 33:26–35. doi:10.1093/eurheartj/ehr186
Harris KM, Braverman AC, Eagle KA et al (2012) Acute aortic intramural hematoma: an analysis from the international registry of acute aortic dissection. Circulation 126:S91–S96. doi:10.1161/CIRCULATIONAHA.111.084541
Kruse MJ, Johnson PT, Fishman EK, Zimmerman SL (2013) Aortic intramural hematoma: review of high-risk imaging features. J Cardiovasc Comput Tomogr 7:267–272. doi:10.1016/j.jcct.2013.04.001
Chao CP, Walker TG, Kalva SP (2009) Natural history and ct appearances of aortic intramural hematoma. Radiographics 29:791–804. doi:10.1148/rg.293085122
Kitai T, Kaji S, Yamamuro A et al (2011) Detection of intimal defect by 64-row multidetector computed tomography in patients with acute aortic intramural hematoma. Circulation 124:S174–S178. doi:10.1161/CIRCULATIONAHA.111.037416
Song JK (2011) Aortic intramural hematoma: aspects of pathogenesis. Herz 36:488–497. doi:10.1007/s00059-011-3501-0
Park KH, Lim C, Choi JH et al (2008) Prevalence of aortic intimal defect in surgically treated acute type A intramural hematoma. Ann Thorac Surg 86:1494–1500. doi:10.1016/j.athoracsur.2008.06.061
Uchida K, Imoto K, Karube N et al (2013) Intramural haematoma should be referred to as thrombosed-type aortic dissection. Eur J Cardiothorac Surg 44:366–369. doi:10.1093/ejcts/ezt040
Hayashi H, Matsuoka Y, Sakamoto I et al (2000) Penetrating atherosclerotic ulcer of the aorta: imaging features and disease concept. Radiographics 20:995–1005. doi:10.2214/AJR.08.2073
Siriapisith T, Wasinrat J, Slisatkorn W (2010) Computed tomography of aortic intramural hematoma and thrombosed dissection. Asian Cardiovasc Thorac Ann 18:456–463. doi:10.1177/0218492310380473
Sebastià C, Evangelista A, Quiroga S et al (2012) Predictive value of small ulcers in the evolution of acute type B intramural hematoma. Eur J Radiol 81:1569–1574. doi:10.1016/j.ejrad.2011.04.055
Ueda T, Chin A, Petrovitch I, Fleischmann D (2012) A pictorial review of acute aortic syndrome: discriminating and overlapping features as revealed by ECG-gated multidetector-row CT angiography. Insights Imaging 3:561–571. doi:10.1007/s13244-012-0195-7
Souza D, Ledbetter S (2012) Diagnostic errors in the evaluation of nontraumatic aortic emergencies. Semin Ultrasound CT MR 33:318–336. doi:10.1053/j.sult.2012.02.001
Knollmann FD, Lacomis JM, Ocak I, Gleason T (2013) The role of aortic wall CT attenuation measurements for the diagnosis of acute aortic syndromes. Eur J Radiol 82:2392–2398. doi:10.1016/j.ejrad.2013.09.007
Kitai T, Kaji S, Yamamuro A et al (2010) Impact of new development of ulcer-like projection on clinical outcomes in patients with type B aortic dissection with closed and thrombosed false lumen. Circulation 122:S74–S80. doi:10.1161/CIRCULATIONAHA.109.92751720)
Hoey ETD, Wai D, Ganeshan A, Watkin RW (2012) Aortic intramural haematoma: pathogenesis, clinical features and imaging evaluation. Postgrad Med J 88:661–667. doi:10.1136/postgradmedj-2011-130677
Sueyoshi E, Matsuoka Y, Imada T et al (2002) New development of an ulcer like projection in aortic intramural hematoma: CT evaluation. Radiology 224:536–541. doi:10.1148/radiol.2242011009
Lee YK, Seo JB, Jang YM et al (2007) Acute and chronic complications of aortic intramural hematoma on follow-up computed tomography: incidence and predictor analysis. J Comput Assist Tomogr 31:435–440
Bosma MS, Quint LE, Williams DM, Patel HJ, Jiang Q, Myles JD (2009) Ulcer like projections developing in noncommunicating aortic dissections: CT findings and natural history. AJR 193:895–905. doi:10.2214/AJR.08.2073
Schlatter T, Auriol J, Marcheix B et al (2011) Type B intramural hematoma of the aorta: evolution and prognostic value of intimal erosion. J Vasc Interv Radiol 22:533–541. doi:10.1016/j.jvir.2010.10-028
Rajiah P (2013) CT and MRI in the evaluation of thoracic aortic diseases. Int J Vasc Med 2013:797189. doi:10.1155/2013/797189
Coady MA, Rizzo JA, Hammond GL, Pierce JG, Kopf GS, JA Elefteriades (1998) Penetrating ulcer of the thoracic aorta: what is it? How do we recognize it? How do we manage it? J Vasc Surg 27:1006–1016
Evangelista A, Carro A, Moral S et al (2013) Imaging modalities for the early diagnosis of acute aortic syndrome. Nat Rev Cardiol 10:477–486. doi:10.1038/nrcardio.2013.92
D’Ancona G, Amaducci A, Rinaudo A et al (2013) Haemodynamic predictors of a penetrating atherosclerotic ulcer rupture using fluid-structure interaction analysis. Interact CardioVasc Thorac Surg 17(3):576–578. doi:10.1093/icvts/ivt245
Ganaha F, Miller DC, Sugimoto K et al (2002) Prognosis of aortic intramural hematoma with and without penetrating atherosclerotic ulcer. A clinical and radiological analysis. Circulation 106:342–348. doi:10.1161/01.CIR.0000022164.26075.5A
Williams DM, Lee DY, Hamilton BH et al (1997) The dissected aorta. Part III. Anatomy and radiologic diagnosis of branch-vessel compromise. Radiology 203:37–44
Willoteaux S, Lions C, Gaxotte V, Negaiwi Z, Beregi JP (2004) Imaging of aortic dissection by helical computed tomography (CT). Eur Radiol 14:1999–2008
Wu MT, Wu TH, Lee D (2005) Multislice computed tomography of aortic intramural hematoma with progressive intercostal artery tears: the Chinese ring-sword sign. Circulation 111:e92–e93. doi:10.1161/01.CIR.0000154547.65893.45
Williams DM, Cronin P, Dasika N et al (2006) Aortic branch artery pseudoaneurysms accompanying aortic dissection. Part I. Pseudoaneurysm anatomy. J Vasc Interv Radiol 17:765–771
Williams DM, Cronin P, Dasika N et al (2006) Aortic branch artery pseudoaneurysms accompanying aortic dissection. Part II. Distinction from penetrating atherosclerotic ulcers. J Vasc Interv Radiol 17:773–781
Wu MT, Wang YC, Huang YL et al (2011) Intramural blood pools accompanying aortic intramural hematoma: CT appearance and natural course. Radiology 258:705–713. doi:10.1148/radiol.10101270
Valente T, Rossi G, Lassandro F et al (2012) MDCT in diagnosing acute aortic syndromes: reviewing common and less common CT findings. Radiol Med 117:393–409. doi:10.1007/s11547-011-0747-9
Cronin P, Carlos RC, Kazerooni EA et al (2012) Aortic branch artery pseudoaneurysms accompanying aortic dissection. Part III: natural history. J Vasc Interv Radiol 23:859–865. doi:10.1016/j.jvir.2012
Ferro C, Rossi UG, Seitun S et al (2013) Aortic branch artery pseudoaneurysms associated with intramural hematoma: when and how to do endovascular embolization. Cardiovasc Intervent Radiol 36:422–432. doi:10.1007/s00270-012-0512-z
Seitun S, Rossi UG, Cademartiri F et al (2012) MDCT findings of aortic branch artery pseudoaneurysms associated with type B intramural haematoma. Radiol Med 117:789–803. doi:10.1007/s11547-011-0779-1
Svensson LG, Labib SB, Eisenhauer AC, Butterly JR (1999) Intimal tear without hematoma: an important variant of aortic dissection that can elude current imaging techniques. Circulation 99:1331–1336. doi:10.1161/01.CIR.99.10.1331
Erbel R, Alfonso F, Boileau C et al (2001) Diagnosis and management of aortic dissection. Recommendations of the Task Force on Aortic Dissection, European Society of Cardiology. Eur Heart J 22:1642–1681. doi:10.1053/euhj.2001.2782
Chirillo F, Salvador L, Bacchion F et al (2007) Clinical and anatomical characteristics of subtle-discrete dissection of the ascending aorta. Am J Cardiol 100:1314–1319
Labruto F, Blomqvist L, Swedenborg J (2011) Imaging the intraluminal thrombus of abdominal aortic aneurysms: techniques, findings, and clinical implications. J Vasc Interv Radiol 22:1069–1075. doi:10.1016/j.jvir.2011.01.454
Rakita D, Newatia A, Hines JJ et al (2007) Spectrum of CT findings in rupture and impending rupture of abdominal aortic aneurysms. Radiographics 27:497–507. doi:10.1148/rg.272065026
Macedo TA, Stanson AW, Oderich GS et al (2004) Infected aortic aneurysms: imaging findings. Radiology 231:250–257. doi:10.1148/radiol.2311021700
Lee WK, Mossop PJ, Little AF et al (2008) Infected (mycotic) aneurysms: spectrum of imaging appearances and management. Radiographics 28:1853–1868. doi:10.1148/rg.287085054
Kuhlman JE, Pozniak MA, Collins J, Knisely BL (1998) Radiographic and CT findings of blunt chest trauma: aortic injuries and looking beyond them. Radiographics 18:1085–1106
Mirvis SE (2006) Thoracic vascular injury. Radiol Clin N Am 44:181–197
Alkadhi H, Wildermuth S, Desbiolles L et al (2004) Vascular emergencies of the thorax after blunt and iatrogenic trauma: multi–detector row CT and three-dimensional imaging. Radiographics 24:1239–1255
Agarwal PP, Chughtai A, Matzinger FR, Kazerooni EA (2009) Multidetector CT of thoracic aortic aneurysms. Radiographics 29:537–552. doi:10.1148/rg.292075080
Gavant ML (1999) Helical CT grading of traumatic aortic injuries. Impact on clinical guidelines for medical and surgical management. Radiol Clin N Am 37:553–574
Neschis DG, Scalea TM, Flinn WR, Griffith BP (2008) Blunt aortic injury. N Engl J Med 359:1708–1716. doi:10.1056/NEJMra0706159
Lamarche Y, Berger FH, Nicolaou S et al (2012) Vancouver simplified grading system with computed tomographic angiography for blunt aortic injury. J Thorac Cardiovasc Surg 144:347–354. doi:10.1016/j.jtcvs.2011.10.011
Simeone A, Freitas M, Frankel HL (2006) Management options in blunt aortic injury: a case series and literature review. Am Surg 72:25–30
Reddy KN, Matatov T, Doucet LD et al (2013) Grading system modification and management of blunt aortic injury. Chin Med J 126:442–445
Steenburg SD, Ravenel JG, Ikonomidis JS et al (2008) Acute traumatic aortic injury: imaging evaluation and management. Radiology 248:748–762. doi:10.1148/radiol.2483071416
Gunn MLD, Lehnert BE, Lungren RS et al (2014) Minimal aortic injury of the thoracic aorta: imaging appearances and outcome. Emerg Radiol 21:227–233. doi:10.1007/s10140-013-1187-8
Goitein O, Fuhrman CR, Lacomis JM (2005) Incidental finding on MDCT of patent ductus arteriosus: use of CT and MRI to assess clinical importance. Am J Roentgenol 184:1924–1931. doi:10.2214/ajr.184.6.01841924
Hoang JK, Martinez S, Hurwitz LM (2009) MDCT angiography after open thoracic aortic surgery: pearls and pitfalls. Am J Roentgenol 192:W20–W27. doi:10.2214/AJR.08.1364
El-Sherief AH, Wu CC, Schoenhagen P et al (2013) Basics of cardiopulmonary bypass: normal and abnormal postoperative CT appearances. Radiographics 33:63–72. doi:10.1148/rg.331115747
Prescott-Focht JA, Martinez-Jimenez S, Hurwitz LM et al (2013) Ascending thoracic aorta: postoperative imaging evaluation. Radiographics 33:73–85. doi:10.1148/rg.331125090
Valente T, Rossi G, Rea G et al (2014) Multi-detector CT findings of complications of surgical and endovascular treatment of aortic aneurysms. Radiol Clin N Am 52(5) (in press)
White GH, Yu W, May J et al (1997) Endoleak as a complication of endoluminal grafting of abdominal aortic aneurysms: classification, incidence, diagnosis, and management. J Endovasc Surg 4:152–168
Ueda T, Fleischmann D, Dake MD et al (2010) Incomplete endograft apposition to the aortic arch: bird-beak configuration increases risk of endoleak formation after thoracic endovascular aortic repair. Radiology 255:645–652. doi:10.1148/radiol.10091468
Kawajiri H, Oka K, Kanda K, Yaku H (2013) Aneurysm formation at both ends of an endograft associated with maladaptive aortic changes after endovascular aortic repair in a healthy patient. Interact CardioVasc Thorac Surg 17:895–897. doi:10.1093/icvts/ivt336
Chernyak V, Rozenblit AM, Patlas M et al (2006) Type II Endoleak after endoaortic graft implantation: diagnosis with helical CT arteriography. Radiology 240:885–893. doi:10.1148/radiol.2403051013
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Valente, T., Rossi, G., Lassandro, F. et al. MDCT distinguishing features of focal aortic projections (FAP) in acute clinical settings. Radiol med 120, 50–72 (2015). https://doi.org/10.1007/s11547-014-0459-z
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DOI: https://doi.org/10.1007/s11547-014-0459-z