Lyapunov Functions, Stationary Distributions, and Non-equilibrium Potential for Reaction Networks
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- Anderson, D.F., Craciun, G., Gopalkrishnan, M. et al. Bull Math Biol (2015) 77: 1744. doi:10.1007/s11538-015-0102-8
We consider the relationship between stationary distributions for stochastic models of reaction systems and Lyapunov functions for their deterministic counterparts. Specifically, we derive the well-known Lyapunov function of reaction network theory as a scaling limit of the non-equilibrium potential of the stationary distribution of stochastically modeled complex balanced systems. We extend this result to general birth–death models and demonstrate via example that similar scaling limits can yield Lyapunov functions even for models that are not complex or detailed balanced, and may even have multiple equilibria.