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Implantable neurotechnologies: bidirectional neural interfaces—applications and VLSI circuit implementations

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An Erratum to this article was published on 01 January 2016

Abstract

A bidirectional neural interface is a device that transfers information into and out of the nervous system. This class of devices has potential to improve treatment and therapy in several patient populations. Progress in very large-scale integration has advanced the design of complex integrated circuits. System-on-chip devices are capable of recording neural electrical activity and altering natural activity with electrical stimulation. Often, these devices include wireless powering and telemetry functions. This review presents the state of the art of bidirectional circuits as applied to neuroprosthetic, neurorepair, and neurotherapeutic systems.

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Acknowledgments

This work was supported by NRF CRP 10201201 and RO1HL071568. The authors acknowledge Chen Cheng for her help in obtaining the data in Figure 3b, and Matthew Fifer, Janaka Senarathna, and Robert Yaffe for helpful comments and feedback.

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Authors and Affiliations

  1. Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA

    Elliot Greenwald, Matthew R. Masters & Nitish V. Thakor

  2. Singapore Institute for Neurotechnology (SINAPSE), National University of Singapore, Singapore, Singapore

    Nitish V. Thakor

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  1. Elliot Greenwald
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Correspondence to Elliot Greenwald.

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Greenwald, E., Masters, M.R. & Thakor, N.V. Implantable neurotechnologies: bidirectional neural interfaces—applications and VLSI circuit implementations. Med Biol Eng Comput 54, 1–17 (2016). https://doi.org/10.1007/s11517-015-1429-x

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