Abstract
Evaluation of binding between analytes and its relevant ligands on surface plasmon resonance (SPR) biosensor is of considerable importance for accurate determination and screening of an interference in immunosensors. Dengue virus serotype 2 was used as a case study in this investigation. This research work compares and interprets the results obtained from analytical analysis with the experimental ones. Both the theoretical calculations and experimental results are verified with one sample from each category of dengue serotypes 2 (low, mid, and high positive), which have been examined in the database of established laboratorial diagnosis. In order to perform this investigation, the SPR angle variations are calculated, analyzed, and then validated via experimental SPR angle variations. Accordingly, the error ratios of 5.35, 6.54, and 3.72 % were obtained for the low-, mid-, and high-positive-specific immune globulins of patient serums, respectively. In addition, the magnetic fields of the biosensor are numerically simulated to show the effect of different binding mediums.
Similar content being viewed by others
References
Berini P (2009) Long-range surface plasmon polaritons. Adv Opt Photonics 1:484
Bessoff K, Delorey M, Sun W, Hunsperger E (2008) Comparison of two commercially available dengue virus (DENV) NS1 capture enzyme-linked immunosorbent assays using a single clinical sample for diagnosis of acute DENV infection. Clin Vaccine Immunol 15:1513–1518
Bhatia P, Gupta BD (2012) Sensors and actuators B: chemical fabrication and characterization of a surface plasmon resonance based fiber optic urea sensor for biomedical applications. Sens Actuators B Chem 161:434–438
Brenner SC, Scott R (2008) The mathematical theory of finite element methods. Springer, NY
Campbell CT, Kim G (2007) SPR microscopy and its applications to high-throughput analyses of biomolecular binding events and their kinetics. Biomaterials 28:2380–2392
Chhatre A, Solasa P, Sakle S et al (2012) Colloids and surfaces a: physicochemical and engineering aspects color and surface plasmon effects in nanoparticle systems: case of silver nanoparticles prepared by microemulsion route. Coll Surf Physicochem Eng Asp 404:83–92
Clarke DH, Casals J (1958) Techniques for hemagglutination and hemagglutination-inhibition with arthropod-borne viruses. Am J Trop Med Hyg 7:561–573
Dussart P, Petit L, Labeau B et al (2008) Evaluation of two new commercial tests for the diagnosis of acute dengue virus infection using NS1 antigen detection in human serum. PLoS Negl Trop Dis 2:e280
Englebienne P, Van Hoonacker A, Verhas M (2003) Surface plasmon resonance: principles, methods and applications in biomedical sciences. Spectroscopy 17:255–273
Fry SR, Meyer M, Semple MG et al (2011) The diagnostic sensitivity of dengue rapid test assays is significantly enhanced by using a combined antigen and antibody testing approach. PLoS Negl Trop Dis 5:e1199
Garg R (2008) Analytical and computational methods in electromagnetics. Artech house
Guzman MG, Jaenisch T, Gaczkowski R et al (2010) Multi-country evaluation of the sensitivity and specificity of two commercially-available NS1 ELISA assays for dengue diagnosis. PLoS Negl Trop Dis 4(8):e811
Haeberle S, Zengerle R (2007) Microfluidic platforms for lab-on-a-chip applications. Lab Chip 7:1094–1110
GE Healthcare (2008) Biacore 3000 Instrument handbook
J iˇrí Homola (2006) Surface plasmon resonance based sensors
Homola J (2008) Surface Plasmon Resonance sensors for detection of chemical and biological species. Chem Rev 108(2): 462–493
Jahanshahi P, Ghomeishi M, Adikan FRM (2014) Study on Dielectric Function Models for Surface Plasmon Resonance Structure. Sci World J 2014: 503749. doi:10.1155/2014/503749
Jahanshahi P, Parvizi A, Mahamd Adikana FR (2013) Three-dimensional modeling of surface plasmon resonance based biosensor. In: Vitkin A, Amelink A (eds) Novel Biophotonic Techniques and Applications II, SPIE Proceedings, vol 8801. Optical Society of America, p 880109
Jahanshahi P, Zalnezhad E, Sekaran SD et al (2014) Rapid immunoglobulin M-based dengue diagnostic test using surface plasmon. 1–7
Jahanshahi P, Dermosesian E, Mahamd Adikan FR, Yong S (2014) Numerical and analytical investigation of a SPR structure as Biosensor. In: Frontiers in Optics. Optical Society of America, p FTh1E.1. doi:10.1364/FIO.2014.FTh1E.1
Jahn CE, Charkowski AO, Willis DK (2008) Evaluation of isolation methods and RNA integrity for bacterial RNA quantitation. J Microbiol Methods 75:318–324
Kumarasamy V, Chua SK, Hassan Z et al (2007) Evaluating the sensitivity of a commercial dengue NS1 antigen-capture ELISA for early diagnosis of acute dengue virus infection. Singap Med J 48:669–673
Kumbhat S, Sharma K, Gehlot R et al (2010) Surface plasmon resonance based immunosensor for serological diagnosis of dengue virus infection. J Pharm Biomed Anal 52:255–259
Lam SK, Devi S, Pang T (1987) Detection of specific IgM in dengue infection. Southeast Asian J Trop Med Public Health 18:532–538
Lee J-G, Cheong KH, Huh N et al (2006) Microchip-based one step DNA extraction and real-time PCR in one chamber for rapid pathogen identification. Lab Chip 6:886–895
Li YZ, Counor D, Lu P et al (2012) A specific and sensitive antigen capture assay for NS1 protein quantitation in Japanese encephalitis virus infection. J Virol Methods 179:8–16
Liedberg B, Nylander C, Lunström I (1983) Surface plasmon resonance for gas detection and biosensing. Sens Actuators 4:299–304
Margheri G, D’Agostino R, Becucci L et al (2012) Surface plasmon resonance as detection tool for lipids lateral mobility in biomimetic membranes. Biomed Opt Express 3:3119–3126
Micro VII, Technology N (2006) BioMEMS and biomedical
Naimushin AN, Soelberg SD, Nguyen DK et al (2002) Detection of Staphylococcus aureus enterotoxin B at femtomolar levels with a miniature integrated two-channel surface plasmon resonance (SPR) sensor. Biosens Bioelectron 17:573–584
Nunes MRT, Nunes Neto JP, Casseb SMM et al (2011) Evaluation of an immunoglobulin M-specific capture enzyme-linked immunosorbent assay for rapid diagnosis of dengue infection. J Virol Methods 171:13–20
Oliveira LC, da Silva Moreira C, Thirstrup C, Melcher EUK, Lima AMN, Neff H (2013) A surface plasmon resonance biochip that operates both in the angular and wavelength interrogation modes. IEEE Trans Instrum Meas 62(5):1223–1232
Peeling RW, Artsob H, Pelegrino JL et al (2010) Evaluation of diagnostic tests: dengue. Nat Rev Microbiol 8:S30–S37
Piliarik M, Sípová H, Kvasnička P et al (2012) High-resolution biosensor based on localized surface plasmons. Opt Express 20:672–680
Pollet J, Delport F, Janssen KPF et al (2011) Fast and accurate peanut allergen detection with nanobead enhanced optical fiber SPR biosensor. Talanta 83:1436–1441
Schmidt AG, Lee K, Yang PL, Harrison SC (2012) Small-molecule inhibitors of dengue-virus entry. PLoS Pathog 8:e1002627
Shalabney A, Abdulhalim I (2012) Figure-of-merit enhancement of surface plasmon resonance sensors in the spectral interrogation. Opt Lett 37:1175–1177
Tanious Fa, Nguyen B, Wilson WD (2008) Biosensor-surface plasmon resonance methods for quantitative analysis of biomolecular interactions. Methods Cell Biol 84:53–77
Teles FSRR (2011) Biosensors and rapid diagnostic tests on the frontier between analytical and clinical chemistry for biomolecular diagnosis of dengue disease: a review. Anal Chim Acta 687:28–42
Verma R, Gupta BD, Jha R (2011) Sensors and Actuators B: chemical Sensitivity enhancement of a surface plasmon resonance based biomolecules sensor using graphene and silicon layers. Sens Actuators B Chem 160:623–631
Wang SM, Sekaran SD (2010) Evaluation of a commercial SD dengue virus NS1 antigen capture enzyme-linked immunosorbent assay kit for early diagnosis of dengue virus infection. J Clin Microbiol 48:2793–2797
Watanabe K (2011) Model for measurement of water layer thickness under lipid bilayers by surface plasmon resonance. Biomed Opt Express 2:1115–1120
Xu J, Wan J, Yang S et al (2012) A surface plasmon resonance biosensor for direct detection of the rabies virus. Acta Vet Brno 81:107–111
Yager P, Domingo GJ, Gerdes J (2008) Point-of-care diagnostics for global health. Annu Rev Biomed Eng 10:107–144
Yong YK, Thayan R, Chong HT et al (2007) Rapid detection and serotyping of dengue virus by multiplex RT-PCR and real-time SYBR green RT-PCR. Singap Med J 48:662–668
Ziegel E, Press W, Flannery B et al (1987) Numerical recipes: the art of scientific computing. Technometrics 29:501
Acknowledgments
This work has been supported by University of Malaya High Impact Research Grant MOHE-HIRG A000007-50001 and MOHE UM.C/625/1/HIR/H-20001-00-E000053. The authors acknowledge and appreciate the University Malaya Medical Center for providing samples.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Jahanshahi, P., Sekaran, S.D. & Adikan, F.R.M. Optical and analytical investigations on dengue virus rapid diagnostic test for IgM antibody detection. Med Biol Eng Comput 53, 679–687 (2015). https://doi.org/10.1007/s11517-015-1262-2
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11517-015-1262-2