Abstract
Strong photoluminescence enhancement of chemically inert and biocompatible SiC quantum dots (QDs) ensured by their near-field coupling with multipolar localized plasmons is experimentally demonstrated. The main physical mechanisms responsible for this phenomenon are described with the use of three-dimensional FDTD simulations. Nano-Ag/SiNX/glass plasmonic substrates were shown to be efficiently used for significant luminescence enhancement of fibroblast cells labeled with the SiC QDs. The proposed approach allows a plasmon-induced enhancement of fluorescent cell imaging.
References
Okamoto K, Niki I, Shvartser A, Narukawa Y, Mukai T, Scherer A (2004) Surface-plasmon-enhanced light emitters based on InGaN quantum wells. Nat Mater 3:601–605
Pompa PP, Martiradonna L, Torre AD, Sala FD, Manna L, Vittorio M, Calabi F, Cingolani R, Rinaldi R (2006) Metal-enhanced fluorescence of colloidal nanocrystals with nanoscale control. Nat Nanotechnol 1:126–130
Jin Y, Gao X (2009) Plasmonic fluorescent quantum dots. Nat Nanotechnol 4:571–576
Ma X, Tan H, Kipp T, Mews A (2010) Fluorescence enhancement, blinking suppression, and gray states of individual semiconductor nanocrystals close to gold nanoparticles. Nano Lett 10:4166–4174
Tam F, Goodrich GP, Johnson BR, Halas NJ (2007) Plasmonic enhancement of molecular fluorescence. Nano Lett 7:496–501
Atwater HA, Polman A (2010) Plasmonics for improved photovoltaic devices. Nat Mater 9:205–213
Zhang J, Fu Y, Liang D, Zhao RY, Lakowicz JR (2008) Enhanced fluorescence images for labeled cells on silver island films. Langmuir 24:12452–12457
Govorov AO, Richardson HH (2007) Generating heat with metal nanoparticles. NanoToday 2:30–38
Huang X, Qian W, El-Sayed IH, El-Sayed MA (2007) The potential use of the enhanced nonlinear properties of gold nanospheres in photothermal cancer therapy. Lasers Surg Med 39:747–753
Mertens H, Koenderink A, Polman A (2007) Plasmon-enhanced luminescence near noble-metal nanospheres: comparison of exact theory and an improved Gersten and Nitzan model. Phys Rev B 76:115123
Maier SA (2007) Plasmonics: fundamentals and applications, 1st edn. Springer, New York
Chen Y, Munechika K, Ginger DS (2007) Dependence of fluorescence intensity on the spectral overlap between fluorophores and plasmon resonant single silver nanoparticles. Nano Lett 7:690–696
Bharadwaj P, Novotny L (2007) Spectral dependence of single molecule fluorescence enhancement. Opt Express 15:14266
Munechika K, Chen Y, Tillack AF, Kulkarni AP, Plante IJ-L, Munro AM, Ginger DS (2010) Spectral control of plasmonic emission enhancement from quantum dots near single silver nanoprisms. Nano Lett 10:2598–2603
Nychyporuk T, Zakharko Y, Serdiuk T, Marty O, Lemiti M, Lysenko V (2011) Strong photoluminescence enhancement of silicon quantum dots by their near-resonant coupling with multi-polar plasmonic hot spots. Nanoscale 3:2472–2475
Liu N, Prall BS, Klimov VI (2006) Hybrid gold/silica/nanocrystal-quantum-dot superstructures: synthesis and analysis of semiconductor–metal interactions. J Am Chem Soc 128:15362–15363
Zhang J, Fu Y, Lakowicz JR (2011) Fluorescent metal nanoshells: lifetime-tunable molecular probes in fluorescent cell imaging. J Phys Chem C 115:7255–7260
Zhang J, Fu Y, Mei Y, Jiang F, Lakowicz JR (2010) Fluorescent metal nanoshell probe to detect single miRNA in lung cancer cell. Anal Chem 82:4464–4471
Szmacinski H, Ray K, Lakowicz JR (2009) Metal-enhanced fluorescence of tryptophan residues in proteins: application toward label-free bioassays. Anal Biochem 385:358–364
Ray K, Szmacinski H, Lakowicz JR (2009) Enhanced fluorescence of proteins and label-free bioassays using aluminum nanostructures. Anal Chem 81:6049–6054
Bruchez MJ, Moronne M, Gin P, Weiss S, Alivisatos AP (1998) Semiconductor nanocrystals as fluorescent biological labels. Science 281:2013–2016
Alivisatos P (2004) The use of nanocrystals in biological detection. Nat Biotechnol 22:47–52
Derfus AM, Chan WCW, Bhatia SN (2004) Probing the cytotoxicity of semiconductor quantum dots. Nano Lett 4:11–18
Botsoa J, Lysenko V, Géloën A, Marty O, Bluet JM, Guillot G (2008) Application of 3C-SiC quantum dots for living cell imaging. Appl Phys Lett 92:173902
Fan J, Li H, Jiang J, So LKY, Lam YW, Chu PK (2008) 3C-SiC nanocrystals as fluorescent biological labels. Small 4:1058–1062
Mognetti B, Barberis A, Marino S, Carlo FD, Lysenko V, Marty O, Géloën A (2010) Preferential killing of cancer cells using silicon carbide quantum dots. J Nanosci Nanotechnol 10:7971–7975
Park NM, Choi CJ, Seong TY, Park SJ (2001) Quantum confinement in amorphous silicon quantum dots embedded in silicon nitride. Phys Rev Lett 86:1355–1357
Lelièvre JF, Torre JD, Kaminski A, Bremond G, Lemiti M, Bouayadi RE, Araujo D, Epicier T, Monna R, Pirot M, Ribeyron PJ, Jaussaud C (2006) Correlation of optical and photoluminescence properties in amorphous SiNx:H thin films deposited by PECVD or UVCVD. Thin Solid Films 511–512:103–107
Nychyporuk T, Zhou Z, Fave A, Lemiti M, Bastide S (2010) Electroless deposition of Ag nanoparticles on the surface of SiNx:H dielectric layers. Sol Energy Mater Sol Cells 94:2314–2317
Palik ED (1985) Handbook of optical constants of solids. Academic, Orlando
Yan JY, Zhang W, Duan S, Zhao XG, Govorov A (2008) Optical properties of coupled metal–semiconductor and metal-molecule nanocrystal complexes: role of multipole effects. Phys Rev B 77:165301
Mo C, Zhang L, Xie C, Wang T (1993) Luminescence of nanometer-sized amorphous silicon nitride solids. J Appl Phys 73:5185
Wang J, Xiong SJ, Wu XL, Li TH, Chu PK (2010) Glycerol-bonded 3C-SiC nanocrystal solid films exhibiting broad and stable violet to blue-green emission. Nano Lett 10:1466–1471
Zakharko Y, Botsoa J, Alekseev S, Lysenko V, Bluet JM, Marty O, Skryshevsky VA, Guillot G (2010) Influence of the interfacial chemical environment on the luminescence of 3C-SiC nanoparticles. J Appl Phys 107:013503
Gartia MR, Hsiao A, Sivaguru M, Chen Y, Liu GL (2011) Enhanced 3D fluorescence live cell imaging on nanoplasmonic substrate. Nanotechnology 22:365203
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Zakharko, Y., Serdiuk, T., Nychyporuk, T. et al. Plasmon-Enhanced Photoluminescence of SiC Quantum Dots for Cell Imaging Applications. Plasmonics 7, 725–732 (2012). https://doi.org/10.1007/s11468-012-9364-2
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DOI: https://doi.org/10.1007/s11468-012-9364-2