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Wirkungsmechanismus von Canagliflozin

Mechanism of action for canagliflozin

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Notes

  1. Die Spitzenplasmakonzentration beim Menschen nach Einnahme der zugelassenen Maximaldosis von 300 mg Canagliflozin liegt bei ~10 µmol/l.

Literatur

  1. Fullerton MD, Galic S, Marcinko K, Sikkema S, Pulinilkunnil T, Chen ZP, O’Neill HM, Ford RJ, Palanivel R, O’Brien M, Hardie DG, Macaulay SL, Schertzer JD, Dyck JR, van Denderen BJ, Kemp BE, Steinberg GR (2013) Single phosphorylation sites in Acc1 and Acc2 regulate lipid homeostasis and the insulin-sensitizing effects of metformin. Nat Med 19(12):1649–1654

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Authors and Affiliations

  1. Klinik für Endokrinologie und Diabetologie, Universitätsklinik Düsseldorf, Moorenstraße 5, 40225, Düsseldorf, Deutschland

    S. Kahl

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  1. S. Kahl
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Correspondence to S. Kahl.

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Kahl, S. Wirkungsmechanismus von Canagliflozin. Diabetologe 12, 434–436 (2016). https://doi.org/10.1007/s11428-016-0131-4

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