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Copper-catalyzed arenes amination with saccharins

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Abstract

A novel copper-catalyzed direct C-N formation reaction of simple arenes with cheap and pharmacological saccharin derivatives under relatively mild conditions was developed with arenes as limiting reagents. This work provided a new method for oxidative coupling of aromatic C(sp2)-H bonds and N-H bonds.

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Authors and Affiliations

  1. Department of Chemistry, Northeast Normal University, Changchun, 130024, China

    Yan Li & Qian Zhang

  2. College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang, 455000, China

    Kai Sun

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  1. Kai Sun
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  2. Yan Li
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  3. Qian Zhang
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Correspondence to Yan Li or Qian Zhang.

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Sun, K., Li, Y. & Zhang, Q. Copper-catalyzed arenes amination with saccharins. Sci. China Chem. 58, 1354–1358 (2015). https://doi.org/10.1007/s11426-015-5385-y

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