, Volume 7, Issue 3, pp 290-294
Date: 27 Sep 2011

Hospital for Special Surgery 2011 Resident and Fellow Research Presentations Award-Winning Abstracts

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Lewis Clark Wagner Award in Orthopaedic Excellence in Orthopaedic Clinical/Translational Research

Recipient: Han Jo Kim, MD

Title: The Efficacy of a Thrombin-Based Hemostatic Agent in Minimizing Blood Loss in Total Knee Arthroplasty—A Randomized Control Trial

Han Jo Kim MD, M Robson Fraser MD, Barbara Kahn RN, Stephen Lyman PhD, Mark P. Figgie MD

Introduction: Blood loss following total knee arthroplasty can lead to significant morbidity and transfusion requirements elevating healthcare costs. Efforts have been made to use hemostatic agents to minimize blood loss and decrease transfusion rates. Floseal (F) is a thrombin-based hemostatic agent with unknown efficacy in achieving these goals in total knee arthroplasty patients.

Materials and Methods: We performed a prospective randomized controlled trial on F in patients undergoing total knee arthroplasty with the primary endpoint of assessing blood loss measured through drain output. Patient demographic information, operative side, diagnos ...