, Volume 6, Issue 2, pp 206-213
Date: 30 Jul 2010

Large-Vessel Granulomatous Vasculitis in Crohn’s Disease

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Case presentation

A 28-year-old African-American female with a past medical history of Crohn’s disease and associated arthritis was evaluated for chest pain of 5-month duration that had become worse over the previous week. Her past medical history was significant for Crohn’s disease diagnosed 7 years earlier when she presented with nonbloody diarrhea after a trip to Kenya. She underwent a colonoscopy that confirmed the diagnosis, and she was treated with mesalamine and steroids for 1 year at an outside institution. She had one flare of her bowel disease 2 years later, which required hospitalization for 2 days and was treated briefly with oral steroids. She also underwent a liver biopsy because of abnormal liver enzymes. This revealed primary sclerosing cholangitis which was not specifically treated at that time.

Ten months prior to this presentation, the patient was admitted with a threatened abortion at 13 weeks of gestation along with an asymmetric polyarthritis of the fingers, wrists, ...

Each author certifies that he or she has no commercial associations (e.g., consultancies, stock ownership, equity interest, patent/licensing arrangements, etc.) that might pose a conflict of interest in connection with the submitted article.
Each author certifies that his or her institution has approved the reporting of this case and that all investigations were conducted in conformity with ethical principles of research.