HSS Journal

, Volume 6, Issue 2, pp 155–159

A Randomized Controlled Trial of Intraarticular Ropivacaine for Pain Management Immediately Following Total Knee Arthroplasty


  • Adam S. Rosen
    • Division of Orthopaedic SurgeryScripps Clinic
    • Division of Orthopaedic SurgeryScripps Clinic
  • Pamela A. Pulido
    • Shiley Center for Orthopaedic Research and Education at Scripps ClinicScripps Health
  • Tricia L. Chaffee
    • Division of Orthopaedic SurgeryScripps Clinic
  • Steven N. Copp
    • Division of Orthopaedic SurgeryScripps Clinic
Original Article

DOI: 10.1007/s11420-010-9155-2

Cite this article as:
Rosen, A.S., Colwell, C.W., Pulido, P.A. et al. HSS Jrnl (2010) 6: 155. doi:10.1007/s11420-010-9155-2


Total knee arthroplasty (TKA) is a commonly performed procedure for the treatment of end-stage arthritis of the knee. Pain control following TKA is difficult to manage in some patients. We examined the use of a postoperative intraarticular injection of 100 mL of 0.2% (200 mg) ropivacaine in a double-blind, prospective, placebo-controlled pilot study to evaluate its use as a pain control modality. All patients received general anesthesia. Postoperatively, patients were placed on intravenous patient-controlled analgesia with morphine. The ropivacaine group showed an early trend in lower visual analog scale (VAS) scores when compared with the placebo group. Patients receiving ropivacaine used a similar amount of narcotics compared with the placebo group. Intraarticular ropivacaine used for pain control after TKA demonstrated no statistically significant difference in lowering VAS scores or narcotic usage; therefore, intraarticular ropivacaine as a single modality is not recommended for effective pain management.


total knee arthroplastyropivacaineintraarticular injectionpain controlrandomized controlled trial

Copyright information

© Hospital for Special Surgery 2010