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Hair growth regulation by the extract of aromatic plant Erica multiflora

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Abstract

Hair growth problems can affect human physical and mental health and are of particular relevance during the aging process. In an effort to resolve such problems, we attempted to find plants having hair growth regulation activity and thus collected plant extracts from Tunisia for bioprospecting purposes. Among them, we investigated the Erica multiflora extract to evaluate the hair growth promotion activity by using the MTT (3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide) assay and cell cycle assay on human dermal papilla cells in vitro and an administration assay on mouse dorsal skin in vivo. The results showed that the Erica multiflora extract promotes dermal papilla cell growth and cell cycle with high activity, and induced hair growth in vivo by induction of anagen phase from telogen phase.

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Acknowledgments

This research was performed under the General Framework Agreement on Science and Technology Cooperation between the Ministry of Scientific Research, Technology and Competency Development (MRSTDC) of the Republic of Tunisia and the Alliance for Research on North Africa (ARENA) of the University of Tsukuba, Japan. The agreement, signed on 6 June 2005, is in-line with the UN Convention on Biological Diversity.

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Authors and Affiliations

  1. Alliance for Research on North Africa (ARENA), Graduate School of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8572, Japan

    Mitsuko Kawano, Junkyu Han & Hiroko Isoda

  2. Bordj Cedria Technopark, BP95, 2050, Hammam-Lif, Tunisia

    Mohamed Elyes Kchouk

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  1. Mitsuko Kawano
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  2. Junkyu Han
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  3. Mohamed Elyes Kchouk
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  4. Hiroko Isoda
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Correspondence to Hiroko Isoda.

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Kawano, M., Han, J., Kchouk, M.E. et al. Hair growth regulation by the extract of aromatic plant Erica multiflora . J Nat Med 63, 335–339 (2009). https://doi.org/10.1007/s11418-009-0324-x

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  • DOI: https://doi.org/10.1007/s11418-009-0324-x

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