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Interaction of age, cognitive function, and gait performance in 50–80-year-olds

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Abstract

The variability of walking gait timing increases with age and is strongly related to fall risk. The purpose of the study was to examine the interaction of age, cognitive function, and gait performance during dual-task walking. Forty-two, healthy men and women, 50–80 years old, completed the Mini-Mental State Exam (MMSE) and Trail Making Test (TMT) to assess cognitive performance and were separated into groups by decade of life. They then performed dual-task walking, at a self-selected pace, on an instrumented treadmill during three cognitive loading conditions: (1) no cognitive load, (2) subtraction from 100 by 1s, and (3) subtraction from 100 by 3s. The treadmill recorded spatiotemporal gait parameters that were used to calculate the mean and coefficient of variation for each variable over ten strides. Time to complete the TMT was positively correlated with age, stride time, double-limb support time, and mediolateral instability and was inversely correlated with single-limb support time. Subjects in their 70s increased their stride time and double-limb support time during the most challenging dual-task condition (subtraction by 3s), whereas subjects in their 50s and 60s did not. Across conditions, the variability of stride length, stride time, and single-limb support time was greatest in the 70s. Mediolateral instability increased only for subjects in their 70s in the subtraction by 3s condition. Reduced cognitive function with age makes it difficult for older adults to maintain a normal, rhythmical gait pattern while performing a cognitive task, which may place them at greater risk for falling.

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References

  • AGS (2001) Guideline for the prevention of falls in older persons. American Geriatrics Society, British Geriatrics Society, and American Academy of Orthopaedic Surgeons Panel on Falls Prevention. J Am Geriatr Soc 49(5):664–672

    Article  Google Scholar 

  • Azar GJ, Lawton AH (1964) Gait and stepping as factors in the frequent falls of elderly women. Gerontologist 4:83–84

    Article  CAS  PubMed  Google Scholar 

  • Brach JS, Berthold R, Craik R, VanSwearingen JM, Newman AB (2001) Gait variability in community-dwelling older adults. J Am Geriatr Soc 49(12):1646–1650

    Article  CAS  PubMed  Google Scholar 

  • Brach JS, Berlin JE, VanSwearingen JM, Newman AB, Studenski SA (2005) Too much or too little step width variability is associated with a fall history in older persons who walk at or near normal gait speed. J Neuroeng Rehabil 2:21. doi:10.1186/1743-0003-2-21

    Article  PubMed Central  PubMed  Google Scholar 

  • Brach JS, Perera S, Studenski S, Newman AB (2008) The reliability and validity of measures of gait variability in community-dwelling older adults. Arch Phys Med Rehabil 89(12):2293–2296. doi:10.1016/j.apmr.2008.06.010

    Article  PubMed Central  PubMed  Google Scholar 

  • Buckner RL (2004) Memory and executive function in aging and AD: multiple factors that cause decline and reserve factors that compensate. Neuron 44(1):195–208. doi:10.1016/j.neuron.2004.09.006

    Article  CAS  PubMed  Google Scholar 

  • Coppin AK, Shumway-Cook A, Saczynski JS, Patel KV, Ble A, Ferrucci L, Guralnik JM (2006) Association of executive function and performance of dual-task physical tests among older adults: analyses from the InChianti study. Age Ageing 35(6):619–624. doi:10.1093/ageing/afl107

    Article  PubMed Central  PubMed  Google Scholar 

  • Dubost V, Kressig RW, Gonthier R, Herrmann FR, Aminian K, Najafi B, Beauchet O (2006) Relationships between dual-task related changes in stride velocity and stride time variability in healthy older adults. Hum Mov Sci 25(3):372–382. doi:10.1016/j.humov.2006.03.004

    Article  PubMed  Google Scholar 

  • Folstein MF, Folstein SE, McHugh PR (1975) Mini-mental state”. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12(3):189–198

    Article  CAS  PubMed  Google Scholar 

  • Gabell A, Nayak US (1984) The effect of age on variability in gait. J Gerontol 39(6):662–666

    Article  CAS  PubMed  Google Scholar 

  • Galna B, Lord S, Rochester L (2013) Is gait variability reliable in older adults and Parkinson’s disease? Towards an optimal testing protocol. Gait Posture 37(4):580–585. doi:10.1016/j.gaitpost.2012.09.025

    Article  PubMed  Google Scholar 

  • Giakas G, Baltzopoulos V (1997) Time and frequency domain analysis of ground reaction forces during walking: an investigation of variability and symmetry. Gait Posture 5:189–197

    Article  Google Scholar 

  • Guimaraes RM, Isaacs B (1980) Characteristics of the gait in old people who fall. Int Rehabil Med 2(4):177–180

    CAS  PubMed  Google Scholar 

  • Guralnik JM, Simonsick EM, Ferrucci L, Glynn RJ, Berkman LF, Blazer DG, Scherr PA, Wallace RB (1994) A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol 49(2):M85–94

    Article  CAS  PubMed  Google Scholar 

  • Guralnik JM, Ferrucci L, Pieper CF, Leveille SG, Markides KS, Ostir GV, Studenski S, Berkman LF, Wallace RB (2000) Lower extremity function and subsequent disability: consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery. J Gerontol A Biol Sci Med Sci 55(4):M221–231

    Article  CAS  PubMed  Google Scholar 

  • Hausdorff JM (2005) Gait variability: methods, modeling and meaning. J Neuroeng Rehabil 2:19. doi:10.1186/1743-0003-2-19

    Article  PubMed Central  PubMed  Google Scholar 

  • Hausdorff JM, Edelberg HK, Mitchell SL, Goldberger AL, Wei JY (1997) Increased gait unsteadiness in community-dwelling elderly fallers. Arch Phys Med Rehabil 78(3):278–283

    Article  CAS  PubMed  Google Scholar 

  • Hausdorff JM, Ashkenazy Y, Peng CK, Ivanov PC, Stanley HE, Goldberger AL (2001a) When human walking becomes random walking: fractal analysis and modeling of gait rhythm fluctuations. Physica A 302(1–4):138–147

    Article  CAS  PubMed  Google Scholar 

  • Hausdorff JM, Rios DA, Edelberg HK (2001b) Gait variability and fall risk in community-living older adults: a 1-year prospective study. Arch Phys Med Rehabil 82(8):1050–1056. doi:10.1053/apmr.2001.24893

    Article  CAS  Google Scholar 

  • Herman T, Mirelman A, Giladi N, Schweiger A, Hausdorff JM (2010a) Executive control deficits as a prodrome to falls in healthy older adults: a prospective study linking thinking, walking, and falling. J Gerontol A Biol Sci Med Sci 65(10):1086–1092. doi:10.1093/gerona/glq077

    Article  Google Scholar 

  • Herman T, Mirelman A, Giladi N, Schweiger A, Hausdorff JM (2010b) Executive control deficits as a prodrome to falls in healthy older adults: a prospective study linking thinking, walking, and falling. J Gerontol A: Biol Med Sci 65(10):1086–1092. doi:10.1093/gerona/glq077

    Article  Google Scholar 

  • Hester AL, Wei F (2013) Falls in the community: state of the science. Clin Interv Aging 8:675–679. doi:10.2147/CIA.S44996

    Article  PubMed Central  PubMed  Google Scholar 

  • Hollman JH, Kovash FM, Kubik JJ, Linbo RA (2007) Age-related differences in spatiotemporal markers of gait stability during dual task walking. Gait posture 26(1):113–119. doi:10.1016/j.gaitpost.2006.08.005

    Article  PubMed  Google Scholar 

  • Hollman JH, Childs KB, McNeil ML, Mueller AC, Quilter CM, Youdas JW (2010) Number of strides required for reliable measurements of pace, rhythm and variability parameters of gait during normal and dual task walking in older individuals. Gait Posture 32(1):23–28. doi:10.1016/j.gaitpost.2010.02.017

    Article  PubMed  Google Scholar 

  • Ko SU, Hausdorff JM, Ferrucci L (2010) Age-associated differences in the gait pattern changes of older adults during fast-speed and fatigue conditions: results from the Baltimore longitudinal study of ageing. Age Ageing 39(6):688–694. doi:10.1093/ageing/afq113

    Article  PubMed Central  PubMed  Google Scholar 

  • Lajoie Y, Teasdale N, Bard C, Fleury M (1993) Attentional demands for static and dynamic equilibrium. Exp Brain Res Exp Hirnforsch Exp Cerebrale 97(1):139–144

    CAS  Google Scholar 

  • LaPointe LL, Stierwalt JA, Maitland CG (2010) Talking while walking: cognitive loading and injurious falls in Parkinson’s disease. Int J Speech Lang Pathol 12(5):455–459. doi:10.3109/17549507.2010.486446

    Article  PubMed  Google Scholar 

  • LaRoche DP, Millett ED, Kralian RJ (2011) Low strength is related to diminished ground reaction forces and walking performance in older women. Gait posture 33(4):668–672. doi:10.1016/j.gaitpost.2011.02.022

    Article  PubMed Central  PubMed  Google Scholar 

  • LaRoche DP, Cook SB, Mackala K (2012) Strength asymmetry increases gait asymmetry and variability in older women. Med Sci Sports Exerc. doi:10.1249/MSS.0b013e31825e1d31

    PubMed Central  PubMed  Google Scholar 

  • Lord S, Howe T, Greenland J, Simpson L, Rochester L (2011) Gait variability in older adults: a structured review of testing protocol and clinimetric properties. Gait Posture 34(4):443–450. doi:10.1016/j.gaitpost.2011.07.010

    Article  PubMed  Google Scholar 

  • Lundin-Olsson L, Nyberg L, Gustafson Y (1997) “Stops walking when talking” as a predictor of falls in elderly people. Lancet 349(9052):617. doi:10.1016/S0140-6736(97)24009-2

    Article  CAS  PubMed  Google Scholar 

  • Montero-Odasso M, Bergman H, Phillips NA, Wong CH, Sourial N, Chertkow H (2009) Dual-tasking and gait in people with mild cognitive impairment. The effect of working memory. BMC Geriatr 9:41

    Article  PubMed Central  PubMed  Google Scholar 

  • Parvataneni K, Ploeg L, Olney SJ, Brouwer B (2009) Kinematic, kinetic and metabolic parameters of treadmill versus overground walking in healthy older adults. Clinical Biomech 24(1):95–100. doi:10.1016/j.clinbiomech.2008.07.002

    Article  Google Scholar 

  • Priest AW, Salamon KB, Hollman JH (2008) Age-related differences in dual task walking: a cross sectional study. J Neuroeng Rehabil 5:29. doi:10.1186/1743-0003-5-29

    Article  PubMed Central  PubMed  Google Scholar 

  • Regnaux JP, Roberston J, Smail DB, Daniel O, Bussel B (2006) Human treadmill walking needs attention. J Neuroeng Rehabil 3:19. doi:10.1186/1743-0003-3-19

    Article  PubMed Central  PubMed  Google Scholar 

  • Rossat A, Fantino B, Nitenberg C, Annweiler C, Poujol L, Herrmann FR, Beauchet O (2010) Risk factors for falling in community-dwelling older adults: which of them are associated with the recurrence of falls? J Nutr Health Aging 14(9):787–791

    Article  CAS  PubMed  Google Scholar 

  • Royall DR, Lauterbach EC, Cummings JL, Reeve A, Rummans TA, Kaufer DI, LaFrance WC Jr, Coffey CE (2002) Executive control function: a review of its promise and challenges for clinical research. A report from the Committee on Research of the American Neuropsychiatric Association. J Neuropsychiatry Clin Neurosci 14(4):377–405

    Article  PubMed  Google Scholar 

  • Sanchez-Cubillo I, Perianez JA, Adrover-Roig D, Rodriguez-Sanchez JM, Rios-Lago M, Tirapu J, Barcelo F (2009) Construct validity of the Trail Making Test: role of task-switching, working memory, inhibition/interference control, and visuomotor abilities. J Int Neuropsychol Soc 15(3):438–450. doi:10.1017/S1355617709090626

    Article  CAS  PubMed  Google Scholar 

  • Siu KC, Chou LS, Mayr U, Donkelaar P, Woollacott MH (2008) Does inability to allocate attention contribute to balance constraints during gait in older adults? The journals of gerontology Series A. Biol Sci Med Sci 63(12):1364–1369

    Google Scholar 

  • Springer S, Giladi N, Peretz C, Yogev G, Simon ES, Hausdorff JM (2006) Dual-tasking effects on gait variability: the role of aging, falls, and executive function. Mov Disord 21(7):950–957. doi:10.1002/mds.20848

    Article  PubMed  Google Scholar 

  • Srygley JM, Mirelman A, Herman T, Giladi N, Hausdorff JM (2009) When does walking alter thinking? Age and task associated findings. Brain Res 1253:92–99. doi:10.1016/j.brainres.2008.11.067

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  • Tombaugh TN (2004) Trail Making Test A and B: normative data stratified by age and education. Arch Clin Neuropsychol 19(2):203–214. doi:10.1016/S0887-6177(03)00039-8

    Article  PubMed  Google Scholar 

  • Van Emmerik RE, Wagenaar RC, Winogrodzka A, Wolters EC (1999) Identification of axial rigidity during locomotion in Parkinson disease. Arch Phys Med Rehabil 80(2):186–191

    Article  PubMed  Google Scholar 

  • van Iersel MB, Ribbers H, Munneke M, Borm GF, Rikkert MG (2007) The effect of cognitive dual tasks on balance during walking in physically fit elderly people. Arch Phys Med Rehabil 88(2):187–191. doi:10.1016/j.apmr.2006.10.031

    Article  PubMed  Google Scholar 

  • Verhaeghen P, Cerella J (2002) Aging, executive control, and attention: a review of meta-analyses. Neurosci Biobehav Rev 26(7):849–857

    Article  PubMed  Google Scholar 

  • Winter DA, Patla AE, Frank JS, Walt SE (1990) Biomechanical walking pattern changes in the fit and healthy elderly. Phys Ther 70(6):340–347

    CAS  PubMed  Google Scholar 

  • Woollacott M, Shumway-Cook A (2002) Attention and the control of posture and gait: a review of an emerging area of research. Gait Posture 16(1):1–14

    Article  PubMed  Google Scholar 

  • Ybarra O, Burnstein E, Winkielman P, Keller MC, Manis M, Chan E, Rodriguez J (2008) Mental exercising through simple socializing: social interaction promotes general cognitive functioning. Pers Soc Psychol Bull 34(2):248–259. doi:10.1177/0146167207310454

    Article  PubMed  Google Scholar 

  • Yogev-Seligmann G, Hausdorff JM, Giladi N (2008) The role of executive function and attention in gait. Mov Disord 23(3):329–342. doi:10.1002/mds.21720, quiz 472

    Article  PubMed  Google Scholar 

  • Yogev-Seligmann G, Rotem-Galili Y, Mirelman A, Dickstein R, Giladi N, Hausdorff JM (2010) How does explicit prioritization alter walking during dual-task performance? Effects of age and sex on gait speed and variability. Phys Ther 90(2):177–186. doi:10.2522/ptj.20090043

    Article  PubMed Central  PubMed  Google Scholar 

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Acknowledgments

D.P. LaRoche was supported by the National Center for Advancing Translational Sciences via NIH Grant L30 AG038028-02.

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Authors and Affiliations

  1. Department of Kinesiology, University of New Hampshire, 124 Main Street, Durham, NH, 03824, USA

    Dain P. LaRoche, Brittnee L. Greenleaf & Ronald V. Croce

  2. Department of Psychology, University of New Hampshire, Durham, NH, USA

    Jill A. McGaughy

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  1. Dain P. LaRoche
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  2. Brittnee L. Greenleaf
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Correspondence to Dain P. LaRoche.

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LaRoche, D.P., Greenleaf, B.L., Croce, R.V. et al. Interaction of age, cognitive function, and gait performance in 50–80-year-olds. AGE 36, 9693 (2014). https://doi.org/10.1007/s11357-014-9693-5

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