Abstract
Myofibroma is a rare benign nodular tumor of soft tissues, bones, or internal organs that can affect both children and adults. The solitary form in adults shows a predilection for the subcutaneous tissue in the head and neck region. Intraosseous lesions are more often found in children. Radiographically, the tumor appears as a well-defined unilocular radiolucent lesion located in the mandible, which may simulate cystic or other odontogenic lesions. A careful differential diagnosis needs to be carried out at the clinical, imaging, and histopathologic levels, because the tumor can have overlapping features with more aggressive spindle cell tumors. The present paper discusses the disease characteristics useful for a correct diagnosis with a particular emphasis on radiological features, describes the complete imaging study of a case of adult myofibroma involving the mandible, and reviews the pertinent literature.
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Giuseppe Guglielmi, Laura Guida, Patrizia Bacchini, Lorenzo Lo Muzio, Franco Bertoni, and Lucio Lo Russo declare that they have no conflict of interest.
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All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964 and later versions. Informed consent was obtained from the patient for being included in the study.
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Guglielmi, G., Guida, L., Bacchini, P. et al. Imaging study of myofibroma of the jaws: case report and literature review. Oral Radiol 32, 195–205 (2016). https://doi.org/10.1007/s11282-015-0230-8
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DOI: https://doi.org/10.1007/s11282-015-0230-8