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The relationship between simple renal cysts and glomerular filtration rate in the elderly

  • Nephrology - Original Paper
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Abstract

Purpose

This cross-sectional study aimed to examine the association between the presence of simple renal cyst and glomerular filtration rate (GFR) in a group of elderly patients.

Methods

This study included 207 elderly subjects residing in a nursing home. All subjects underwent ultrasonography examination as well as serum urea and creatinine measurements. Creatinine clearance was calculated according to Cockroft–Gault formula. In addition, demographic data were recorded.

Results

Sixty-six subjects had simple renal cysts, and cysts were more frequent among male patients (43.1 vs. 28.2 %, p = 0.047). In addition, patients with renal cysts were slightly older and had a slightly lower GFR. On the other hand, patients with or without renal cysts did not differ with regard to renal sizes. In univariate analysis, reduced GFR was associated with older age (81.2 ± 5.9 vs. 75.7 ± 5.1 years, p < 0.001) and was more frequent among females (69.2 vs. 52.9 %, p = 0.034). In addition, lower BMI, presence of cyst, lower mean renal length, and lower mean renal thickness were associated with impaired GFR (p < 0.05 for all); however, number or bilaterality of the cysts were not linked with deterioration of GFR. Multivariate analysis identified only female gender (OR 2.4, 95 % CI 1.1–5.1, p = 0.030), a small BMI (<25; OR 6.2, 95 % CI 2.4–15.5, p < 0.001), and advanced age as independent predictors of low GFR. Each year increase in age results in OR 1.2 (95 % CI 1.1–1.3, p < 0.001).

Conclusion

Presence of simple renal cyst does not seem to have an effect on the decline in GFR in elderly patients. Age-related increase in the incidence of renal cysts appears to occur in geriatric population.

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Authors and Affiliations

  1. Department of Nephrology, Taksim Education and Research Hospital, Istanbul, Turkey

    Ali Abbas Ozdemir

  2. Department of Internal Medicine, Taksim Education and Research Hospital, Istanbul, Turkey

    Korhan Kapucu

Authors
  1. Ali Abbas Ozdemir
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  2. Korhan Kapucu
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Corresponding author

Correspondence to Ali Abbas Ozdemir.

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Conflict of interest

Ali Abbas Ozdemir and Korhan Kapucu declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. This article does not contain any studies with animals performed by any of the authors.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Ozdemir, A.A., Kapucu, K. The relationship between simple renal cysts and glomerular filtration rate in the elderly. Int Urol Nephrol 49, 313–317 (2017). https://doi.org/10.1007/s11255-016-1414-9

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  • DOI: https://doi.org/10.1007/s11255-016-1414-9

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