Skip to main content
Log in

Late onset of progressive speech impairment due to tacrolimus-associated leukoencephalopathy after kidney transplantation

  • Nephrology - Letter to the Editor
  • Published:
International Urology and Nephrology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Reyes J, Gayowski T, Fung J, Todo S, Alessiani M, Starzl TE (1990) Expressive dysphasia possibly related to FK506 in two liver transplant recipients. Transplantation 50:1043–1045

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  2. Boeve BF, Kimmel DW, Aronson AE, de Groen PC (1996) Dysarthria and apraxia of speech associated with FK-506 (tacrolimus). Mayo Clin Proc 71:969–972

    Article  CAS  PubMed  Google Scholar 

  3. Bronster DJ, Gurkan A, Buchsbaum MS, Emre S (2000) Tacrolimus-associated mutism after orthotopic liver transplantation. Transplantation 70:979–982

    Article  CAS  PubMed  Google Scholar 

  4. Sokol DK, Molleston JP, Filo RS, Van Valer J, Edwards-Brown M (2003) Tacrolimus (FK506)-induced mutism after liver transplant. Pediatr Neurol 28:156–158

    Article  PubMed  Google Scholar 

  5. Sierra-Hidalgo F, Martínez-Salio A, Moreno-García S, de Pablo-Fernández E, Correas-Callero E, Ruiz-Morales J (2009) Akinetic mutism induced by tacrolimus. Clin Neuropharmacol 32:293–294

    Article  CAS  PubMed  Google Scholar 

  6. Vearrier D, Simpson SE, Greenberg MI (2011) Mutism and persistent dysarthria due to tacrolimus-based immunosuppression following allogeneic liver transplantation. Am J Ther 18:e274–e276

    Article  PubMed  Google Scholar 

  7. Toledo Perdomo K, Navarro Cabello MD, Pérez Sáez MJ, Ramos Pérez MJ, Agüera Morales ML, Aljama García P (2012) Reversible acute encephalopathy with mutism, induced by calcineurin inhibitors after renal transplantation. J Nephrol 25:839–842

    Article  PubMed  Google Scholar 

  8. Bilbao I, Dopazo C, Castells L, Lazaro J, Caralt M, Sapisochin G, Charco R (2014) Immunosuppression based on everolimus in liver transplant recipients with severe early post-transplantation neurotoxicity. Transplant Proc 46:3104–3107

    Article  CAS  PubMed  Google Scholar 

  9. Jeng KS, Chu SH, Huang CC, Lin CK, Lin CC, Chen KH (2014) Loss of speech after living-related donor liver transplantation: detection of the lesion by diffusion tensor image. Transplant Proc 46:880–882

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgments

This work was financially supported by Grant-in-Aid for Scientific Research (Grant No. 26461906), Japan Society for the Promotion of Science.

Conflict of interest

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Kazushige Sato.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sato, K., Miura, Y., Marui, Y. et al. Late onset of progressive speech impairment due to tacrolimus-associated leukoencephalopathy after kidney transplantation. Int Urol Nephrol 47, 1437–1438 (2015). https://doi.org/10.1007/s11255-015-1026-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11255-015-1026-9

Keywords

Navigation