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Factors associated with depression and anxiety in patients with end-stage renal disease receiving maintenance hemodialysis

  • Nephrology - Original Paper
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Abstract

Objectives

To investigate anxiety, depression, and related factors in patients with end-stage renal disease (ESRD) receiving maintenance hemodialysis and provide a reference for the establishment of a healthier life for such patients.

Methods

A total of 81 patients were enrolled in the study. Qualified participants filled out self-rating anxiety scale (SAS) and depression self-assessment scale (SDS) questionnaires as well as assessments of health knowledge and health self-efficacy. Linear regression analysis was performed to relate demographic factors, lifestyle habits, and nutrition parameters to SDS and SAS score indices.

Results

The mean SAS and SDS score indices for the 81 patients were 52.96 and 46.71, respectively; 56 patients (69.1 %) had a depressive disorder (SDS score ≥ 50), and 31 patients (36.9 %) had anxiety symptoms (SAS score ≥ 50). SAS score index correlated with gender (p < .05) and history of alcohol use (p < .01), whereas SDS score index correlated with administration of erythropoietin (EPO) (p < .05) as well as gender and history of alcohol use.

Conclusion

History of alcohol consumption may predict less depressive symptoms and more anxiety among Chinese patients living in a northeastern Chinese city with ESRD. EPO administration may reduce anxiety in patients with ESRD. Female patients were more prone to anxiety, whereas males were more likely to show symptoms of depression. These factors should be evaluated by nephrologists treating patients with ESRD.

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Acknowledgments

We thank Drs. Dong-Xü Hong, Ji-ping Wang, and Xiao-jie Yuan from the Department of Clinical Nutrition at the First Hospital of Jilin University for setting up the diets for the patients in this study.

Conflict of interest

This is not an industry-supported study. The authors have indicated no financial conflicts of interest.

Author information

Authors and Affiliations

  1. Department of Nephrology, First Hospital of Jilin University, 71 Xinmin Street, Changchun, 130021, Jilin Province, China

    Yue Hou, Lizhi Yang, Hao Wu, Ying Xu, Fan Yang & Yujun Du

  2. The Tumor Hospital of Jilin Province, Changchun, Jilin Province, China

    Xiujiang Li

  3. Department of Psychology, First Hospital of Jilin University, 71 Xinmin Street, Changchun, 130021, Jilin Province, China

    Chang Liu

Authors
  1. Yue Hou
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  2. Xiujiang Li
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  3. Lizhi Yang
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  4. Chang Liu
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  5. Hao Wu
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  6. Ying Xu
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  7. Fan Yang
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  8. Yujun Du
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Corresponding author

Correspondence to Yujun Du.

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Hou, Y., Li, X., Yang, L. et al. Factors associated with depression and anxiety in patients with end-stage renal disease receiving maintenance hemodialysis. Int Urol Nephrol 46, 1645–1649 (2014). https://doi.org/10.1007/s11255-014-0685-2

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  • DOI: https://doi.org/10.1007/s11255-014-0685-2

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