Abstract
A cross-sectional study was conducted from March to August 2006 in dairy herds in Fars province, southern Iran to determine the herd-level risk factors for infection with Mycobacterium avium subspecies paratuberculosis (MAP). Statistical analysis using multivariable logistic regression showed that contamination of udders of periparturient cows with manure (OR = 6.4, P = 0.02) and history of having suspected cases of Johne's disease in the herd (OR = 6.7, P = 0.04) were significantly associated with the herd infection status. No relationship between breed, herd size and other management practices with the infection status of the herd were found in this study. Implementing high sanitary measures in the farm, particularly with respect to manure handling and cleaning could be considered as one of the important aspects in controlling disease in the region as well as in the future educational effort.
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References
Anzaby, Y., Tabatabayi, A.H., Asgharzade, M., 2006. A survey of the infection status of Mycobacterium avium paratuberculosis in dairy cattle using PCR and culture of Tabriz region. (In Persian) Iranian Journal of Veterinary science, 2, 297–310.
Beaudeau, F., Belliard, M., Joly, A., Seegers, H., 2007. Reduction in milk yield associated with Mycobacterium avium subspecies paratuberculosis (Map) infection in dairy cows. Veterinary Research, 38, 625–634. doi:10.1051/vetres:2007021
Benedictus, G., Dijkhhuizen, A.A., Stelwagen, J., 1987. Economic losses due to paratuberculosis in dairy cattle. Veterinary Record, 121, 142–146.
Berghaus, R.D., Lombard, J.E., Gardner, I.A., Farver, T.B., 2005. Factor analysis of a Johne’s disease risk assessment questionnaire with evaluation of factor scores and a subset of original questions as predictors of observed clinical paratuberculosis. Preventive Veterinary Medicine, 72, 291–309. doi:10.1016/j.prevetmed.2005.07.011
Gaya, D.R., Black, R.A., MacKenzie, J.F., 2004. Crohn’s disease and MAP. Lancet, 364, 2179. doi:10.1016/S0140-6736(04)17587-9
Gonda, M.G., Chang, Y.M., Shook, G.E., Collins. M.T., Kirkpatrick, B.W., 2007. Effect of Mycobacterium paratuberculosis infection on production, reproduction and health traits in US Holsteins. Preventive Veterinary Medicine 80, 103–119. doi:10.1016/j.prevetmed.2007.01.011
Greenstein, R.J., Collins, M.T., 2004. Emerging pathogens: is Mycobacterium avium subspecies paratuberculosis zoonotic? Lancet 31, 396–397. doi:10.1016/S0140-6736(04)16781-0
Haghkhah, M., Ansari-Lari, M., Novin Baheran, A.M., Bahramy, A., 2008. Herd-level prevalence of Mycobacterium avium subspecies paratuberculosis by bulk-tank milk PCR in Fars province (southern Iran) dairy herds. Preventive Veterinary Medicine, 86, 8–13. doi:10.1016/j.prevetmed.2008.03.010
Johnson-Ifearulundu, Y.J., Kaneene, J.B., 1998. Management-related risk factors for M. paratuberculosis infection in Michigan, USA, dairy herds. Preventive Veterinary Medicine 37, 41–54. doi:10.1016/S0167-5877(98)00110-X
Khodakaram Tafti, A., Rashidi, K., 2000. The Pathology of goat paratuberculosis: gross and histopathological lesions in the intestines and mesenteric lymph nodes. Journal of veterinary medicine. B, Infectious diseases and veterinary public health 47, 487–495. doi:10.1046/j.1439-0450.2000.00375.x
Obasanjo, I.O., Grohn, Y.T., Mohammed, H.O., 1997. Farm factors associated with the presence of Mycobacterium paratuberculosis infection in dairy herds on the New York state Paratuberculosis Control Program. Preventive Veterinary Medicine 32, 243–251. doi:10.1016/S0167-5877(97)00027-5
Pourjafar, M., Badiei, K., 2005. Presence and trace element analysis in cattle affected by paratuberculosis in Yasouj, Iran. 8th International Colloquium on Paratuberculosis, Spain.
Romero, C., Hamdi, A., Valentine, J.F., Naser, S.A., 2005. Evaluation of surgical tissue from patients with Crohn’s disease for the presence of Mycobacterium avium subspecies paratuberculosis DNA by in situ hybridization and nested polymerase chain reaction. Inflammatory bowel diseases 11, 116–125. doi:10.1097/00054725-200502000-00004
Russiter, C.A., Burhans WS., 1996. Farm-specific approach to paratuberculosis (Johne’s disease) control. The Veterinary clinics of North America. Food animal practice 12: 383–415.
Sweeney, R.W., 1996. Transmission of paratuberculosis. The Veterinary clinics of North America. Food animal practice 12: 305–312.
Talatchian, M., First report of Johne’s disease in Iran. 1965. Bulletin - Office international des epizooties 64: 779–82.
Acknowledgments
The authors would like to thank the herd owners for their help and cooperation in collecting management information. This study was supported by Grant No. 84-VE-1780_C308 Shiraz University, Fars, Iran.
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Ansari-Lari, M., Haghkhah, M., Bahramy, A. et al. Risk factors for Mycobacterium avium subspecies paratuberculosis in Fars province (Southern Iran) dairy herds. Trop Anim Health Prod 41, 553–557 (2009). https://doi.org/10.1007/s11250-008-9221-7
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DOI: https://doi.org/10.1007/s11250-008-9221-7