Abstract
Two azido-coordinated Schiff base Cu(II) complexes with the formulae [Cu(L1)(N3)]·MeOH and [Cu(L2)(μ1,1-N3)] n , where L1 is the deprotonated form of 2-chloro-2-[(2-ethylaminoethylimino)methyl]phenol, and L2 is the deprotonated form of 2,4-dibromo-6-[(2-dimethylaminoethylimino)methyl]phenol, have been synthesized and characterized by physico-chemical and spectroscopic methods. The X-ray crystal structures of both complexes have been determined. The Cu atom in [Cu(L1)(N3)]·MeOH is four-coordinate in a square planar geometry, while [Cu(L2)(μ1,1-N3)] n is five-coordinate with a square pyramidal geometry. The molecules in [Cu(L1)(N3)]·MeOH are linked by intermolecular O–H···O and N–H···O hydrogen bonds, forming dimers. The molecules in [Cu(L2)(μ1,1-N3)] n are linked through end-on azido bridges, forming one-dimensional chains. The xanthine oxidase inhibitory activities of both complexes were evaluated.
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Chan PH, Schimidley JW, Fishman RA, Longar SM (1984) Neurology 34:315
Naeff HSD, Franssen MCR, van der Plas HC (1991) Recl Trav Pay-B 110:139
Robins RK, Revankar GR, ÓBrien DE, Springer RH, Novinson T, Albert A, Senga K, Miller JP, Streeter DG (1985) J Heterocycl Chem 22:601
Haberland A, Luther H, Schinker I (1991) Agents Actions 32:96
Hou P, You Z-L, Zhang L, Ma X-L, Ni L-L (2008) Transition Met Chem 33:1013
You Z-L, Zhou P (2008) Transition Met Chem 33:453
You Z-L, Shi D-H, Zhu H-L (2006) Inorg Chem Commun 9:642
Bruker S (2002) SMART and SAINT. Bruker AXS Inc, Madison
Sheldrick GM (1996) SADABS. University of Göttingen, Germany
Sheldrick GM (1997) SHELXTL V5.1, software reference manual. Bruker AXS Inc, Madison
Kong LD, Zhang Y, Pan X, Tan RX, Cheng CHK (2002) Cell Mol Life Sci 57:500
Geary WJ (1971) Coord Chem Rev 7:81
Mukherjee PS, Dalai S, Mostafa G, Lu T-H, Rentschler E, Chaudhuri NR (2001) New J Chem 25:1203
You Z-L, Jiao Q-Z, Niu S-Y, Chi J-Y (2006) Z Anorg Allg Chem 632:2481
Jiang Y-B, Kou H-Z, Wang R-J, Cui A-L (2004) Eur J Inorg Chem 23:4608
You Z-L (2005) Acta Crytallogr C61:m339
Zbiri M, Saha S, Adhikary C, Chaudhuri S, Daul C, Koner S (2006) Inorg Chim Acta 359:1193
Xu H, He C, Sui Y-X, Ren X-M, Guo L-M, Zhang Y-G, Nishihara S, Hosokoshi Y (2007) Polyhedron 26:4463
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This work was financially supported by the Education Office of Liaoning Province (Project No. 2008T107).
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Cui, YQ., You, ZL., Li, XF. et al. Synthesis, crystal structures and xanthine oxidase inhibitory activities of two copper(II) complexes with Schiff bases. Transition Met Chem 35, 159–163 (2010). https://doi.org/10.1007/s11243-009-9309-6
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DOI: https://doi.org/10.1007/s11243-009-9309-6