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Spontaneous coronary thrombosis following thrombolytic therapy for acute cardiovascular accident and stroke: a case study

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Abstract

Cardiac complications following stroke or acute cerebrovascular accidents (CVA) are common; however, many of these complications are asymptomatic and do not cause adverse cardiac effects. Symptomatic events (such as acute myocardial infarction after CVA) rarely occur and are often the result of an underlying cardiac embolic source, such as a left ventricular thrombus. We report a case of spontaneous coronary thrombosis following thrombolytic therapy for acute CVA, and discuss the implication that an underlying systemic pro-thrombotic state may predispose individuals to thrombosis in disparate vascular beds.

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Acknowledgments

The authors wish to thank Susan Quick for outstanding editorial support. This work was supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences, National Institutes of Health, through Grant 1UL1RR033173. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. This work was also supported by resources and/or the use of facilities at the Lexington VA Medical Center.

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  1. Division of Cardiovascular Medicine, The Gill Heart Institute, University of Kentucky, The Lexington VA Medical Center, 900 S. Limestone Street, 326 CTW Building, Lexington, KY, 40536-0200, USA

    Eric L. Wallace & Susan S. Smyth

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  1. Eric L. Wallace
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  2. Susan S. Smyth
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Correspondence to Eric L. Wallace.

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Wallace, E.L., Smyth, S.S. Spontaneous coronary thrombosis following thrombolytic therapy for acute cardiovascular accident and stroke: a case study. J Thromb Thrombolysis 34, 548–551 (2012). https://doi.org/10.1007/s11239-012-0754-2

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