Research on Chemical Intermediates

, Volume 39, Issue 8, pp 3877–3885

Mild preparation of chromeno[2,3-d]pyrimidines catalyzed by Brønsted acidic ionic liquids under solvent-free and ambient conditions


DOI: 10.1007/s11164-012-0889-y

Cite this article as:
Shaterian, H.R. & Aghakhanizadeh, M. Res Chem Intermed (2013) 39: 3877. doi:10.1007/s11164-012-0889-y


Brønsted acidic ionic liquids, namely 2-pyrrolidonium hydrogensulfate, N-methyl-2-pyrrolidonium hydrogensulfate, N-methyl-2-pyrrolidonium dihydrogenphosphate, (4-sulfobutyl)tris(4-sulfophenyl)phosphonium hydrogensulfate, triphenyl(propyl-3-sulfonyl)phosphonium toluenesulfonate, l-prolinium sulfate, and l-prolinium nitrate, catalyzed efficient one-pot pseudo-four-component reaction of salicylaldehydes, malononitrile, and secondary amine for preparation of chromeno[2,3-d]pyrimidines under solvent-free conditions at room temperature. The catalysts show environmentally benign character and can be easily prepared, stored, and recovered without obvious significant loss of activity.


Ionic liquidCatalystSolvent freeSalicylaldehydeChromeno[2,3-d]pyrimidine

Copyright information

© Springer Science+Business Media Dordrecht 2012

Authors and Affiliations

  1. 1.Department of ChemistryFaculty of Sciences, University of Sistan and BaluchestanZahedanIran