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AcOH catalyzed three-component synthesis of spirooxindole derivatives

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Abstract

An efficient one-pot synthesis of hereto unknown indenoquinoline-spirooxindole derivatives by a three-component reaction of isatins, indan-1,3-dione, and 3-aminocyclohex-2-enone under the catalysis of acetic acid was developed. The procedure had the advantages of simplicity and efficiency.

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Acknowledgments

This work was supported by the Foundation of Xi’an Shiyou University (Z08012).

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Authors and Affiliations

  1. College of Chemistry and Chemical Engineering, Xi’an Shiyou University, Xi’an, 710065, China

    Peng Hui Yang, Cheng Tun Qu & Wen Zhen Wang

Authors
  1. Peng Hui Yang
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  2. Cheng Tun Qu
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  3. Wen Zhen Wang
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Correspondence to Peng Hui Yang.

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Yang, P.H., Qu, C.T. & Wang, W.Z. AcOH catalyzed three-component synthesis of spirooxindole derivatives. Res Chem Intermed 39, 463–468 (2013). https://doi.org/10.1007/s11164-012-0570-5

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  • DOI: https://doi.org/10.1007/s11164-012-0570-5

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