Abstract
Rathke's cleft cyst is a non neoplastic lesion remnant of the Rathke's poutch. Symptomatic cysts must be surgically treated. There are no specific neuroradiological features for this lesion. We present a series of 14 symptomatic Rathke's cleft cysts treated with transphenoidal endoscopic technique, and we correlate the MRI intensity images with the intraoperative findings, the pathological analysis, the growth pattern and the recurrence tendency, to understand wether there is a better way to recognize these lesions, especially the asyntomatic ones, that, despite other neoplastic cysts, colud only be observed with a MRI follow up.
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Itoh J, Usui K. An entirely suprasellar symptomatic Rathke's cleft cyst: Case Report. Neurosurgery 1992;30(4):581–585.
Wenger M, Simko M, Markwalder R, Taub E. An entirely suprasellar Rathke's cleft cyst: Case report and review of the literature. J Clin Neurosci 2001;8(6):564–567.
Saeki N, Hoshi S, Sunada S, Sunami K, Yamaura A. Rathke's cleft cyst with a large frontal extention: Unusual shape and pathomechanism of its formation. J Clin Neurosci 2000;7(5):452–464.
Cervoni L, Artico M, Salvati M, Carloia S. Rathke's cleft cyst: A clinical and radiographic review. Ital J Neurol Sci 1997;18:37–40.
El-Mahdy W, Powell M. Transsphenoidal menagement of 28 symptomatic Rathke's Cleft Cyst, with special reference to visual and hormonal recovery. Neurosurgery 1998;42:1.
Ersahin Y, Ozdamar N, Demirtas E, Mutluer S. A case of Rathke's cleft cyst presenting with diabetes insipidus. Clinical Neurol Neurosurg 1995;97(4):317–320.
Fischer EG, DeGirolami U, Suojanem JN. Reversible visual deficittt following debulking of a Rathke's cleft cyst: A tethered chiasm? Case Report. J Neurosurg 1994;81(3):459–462.
Isono M, Kamida T, Kobayashi H, Shimomura T, Matsuyama J. Clinical features of symptomatic Rathke's cleft cyst. Clin Nurol Neurosurg 2001;103(2):96–100.
Keyaki A, Kim YJ, Nebeshima S. Clinical study of symptomatic Rathke cleft cyst. No Shinkei Geka 1999;27(7):625–631.
Mukherjee JJ, Lee CH, Ong PL, Teo J. Panhypopituitarism due to pituitary cyst of Rathke's cleft origin–-two case reports. Ann Acad Med Singapore 2001;30:651–655.
Brassier G, Morandi X, Tayiar E, Riffaud L, Chabert E, Heresbach N, et al. Rathke's cleft cyst: Surgical MRI correlation in 16 symptomatic cases. J Neuroradiol 1999;26(3):162–171.
Daikokuya H, Inoue Y, Nemoto Y, Tashiro T, Shakudo M, Ohata K. Rathke's cleft cyst associated with hypophysitis: MRI. Neuroradiology 2000;42:532–534.
Hayashi Y, Tachibana O, Muramatsu N, Tsuchiya H, Tada M, Arakawa Y, et al. Rathke cleft cyst: MR and biochemical analysis of cyst content. J Comput Ass Tomogr 23(1):34–38.
Kleinschmidt-DeMasters BK, Lillehei KO, Stears JC. The pathologic, Surgical and MR spectrum of Rathke cleft cysts. Surg Neurol 1995;44:19–27.
Naylor MF, Scheithauer BW, Forbes GS, Tomlinson FH, Young WF. Rathke cleft cyst: CT, MR, and pathology of 23 cases. J Comput Assist Tomogr 1995;19(6):853–859.
Oka H, Kawano N, Suwa T, Yada K, Kan S, Kameya T. Radiological study of symptomatic Rathke's cleft cyst. Neurosurgery 1994;35(4):632–637.
Saeki N, Sunami K, Sugaya Y, Yamaura A. MRI findings and clinical manifestations in Rathke's cleft cyst. Acta Neurochir (Wien) 1999;141:1055–1061.
Sugiyama K, Tangawa K, Sakai M, Okuno S, Ohtsubo T, Nakao H, et al. A symptomatic Rathke's cleft cyst: Preoperative diagnosis. Chinese Med J 1998;111(12):1124–1125.
Hama S, Arita K, Nishisaka T, Fukuhara T, Tominaga A, Sugiyama K, et al. Changes in the epithelium of Rathke cleft cyst associated with inflammation. J Neurosurg 2002;96:209–216.
Shin JL, Asa SL, Woodhouse LJ, Smyth HS, Ezzat S. Cystic lesions of the pituitary: Clinicopathological features distinguishing craniopharyngioma, Rathke's cleft cyst, and Arachnoid cyst. J Clin Neurol Metab 1999;84(11):3972–3982.
Sumida M, Arita K, Migita K, Tominaga A, Iida K, Kurisu K. Concomitant pituitary adenoma and Rathke's cleft cyst. Neuroradiology 2001;43:755–759.
Byun WM, Kim OL, Kim D. MR imaging findings of Rathke's cleft cysts: Significance of intracystic nodules. AJNR Am J Neuroradiol 2000;21:485–488.
Macaulay RJB. Ruptured Rathke's cleft cyst: a possible cause of Tolosa-Hunt syndrome. Clin Neuropathol 1997;16(2):98–102.
Nakayama Y, Tanaka A, Naritomi K, Yoshinaga S. Hyponatriemia-induced metabolic encephalopathy caused by Rathke's cleft cyst: a case report. Clin Neurol Neurosurg 1999;101(2):114–117.
Nishioka H, Ito H, Miki T, Hashimoto T, Nojima H, Matsumura H. Rathke's cleft cyst with pituitary apoplexy: case report. Neuroradiology 1999;41(11):832–834.
Roncaroli F, Bacci A, Frank G, Calbucci F. Granulomatous hypophisitis caused by a ruptured intrasellar Rathke's left cyst: Report of a case and review of the literature. Neurosurgery 1998;43:146–149.
Wearne MJ, Barber PC, Johnson AP. Symptomatic Rathke's cleft cyst with hypophisitis. Br J Neurosurg 1995;9:799–803.
Ross DA, Norman D, Wilson CB. Radiologic characteristic and results of surgical management of Rathke's cysts in 43 patients. Neurosurgery 1992;30:173–179.
Mukherjee JJ, Islam N, Kaltsas G, Lowe DG, Charlesworth M, Afshar F, et al. Clinical, radiological and pathological features of patients with Rathke's cleft cyst: Tumors that may recur. J Clin Endocrinol Metab 1997;82(7):2357–2362.
Israel ZH, Yacoub M, Gomori JM, Dotan S, Felling Y, Shoshan Y, et al. Rathke's cleft cyst abscess. Pediatr Neurosurg 2000;33(3):159–161.
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Billeci, D., Marton, E., Tripodi, M. et al. Symptomatic Rathke's Cleft Cysts: A Radiological, Surgical and Pathological Review. Pituitary 7, 131–137 (2004). https://doi.org/10.1007/s11102-005-1755-3
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DOI: https://doi.org/10.1007/s11102-005-1755-3