We present here our results from studies of the pharmacokinetic parameters of the original antituberculosis agent thiozonide, 100-mg capsules (ZAO Farm-Sintez, Moscow) using single increasing doses in different groups of healthy volunteers in a phase I clinical trial.
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References
Tuberculosis in the Russian Federation. Basic Statistical Yearbook on Tuberculosis Used in the Russian Federation, Moscow (2011), p. 402.
WHO Global Tuberculosis Control [in Russian], (2013); URL: http://www.who.int/tb/publications/global report/ru/
M. I. Perel’man, Consilium Med., No. 12, 564 – 568 (2001).
V. Yu. Mishin, Problemy Tuberkuleza, No. 7, 24 – 29 (2003).
M. A. Karachunskii, Rus. Med. Zh., 9(21), 951 – 953 (2001).
V. I. Chukanov, Rus. Med. Zh., 9(21), 954 – 959 (2001).
Yu. M. Repin, Surgical Treatment [in Russian], Gippokrat, St. Petersburg (2007), p. 168.
I. V. Bacharova, M. S. Burenkov, L. N. Lepekha, et al., Tuberkulez i Bolezni Legkikh, No. 6, 46 – 50 (2014).
G. V. Ramenskaya, I. E. Shokhin, L. A. Men’shikova, et al., Khim.-Farm. Zh., 49(3), 46 – 49 (2015).
Federal Law No. 61-FZ “The Circulation of Medicines,” Adopted by resolution of the Government of the Russian Federation, April 12, 2010, Moscow (2010).
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 49, No. 3, pp. 3 – 6, March, 2015.
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Savchenko, A.Y., Men’shikova, L.A., Ramenskaya, G.V. et al. Pharmacokinetic Studies of the Innovative Antituberculosis Drug Thiozonide in Plasma. Pharm Chem J 49, 147–150 (2015). https://doi.org/10.1007/s11094-015-1243-7
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DOI: https://doi.org/10.1007/s11094-015-1243-7