Skip to main content

Advertisement

Log in

Pharmacokinetic Studies of the Innovative Antituberculosis Drug Thiozonide in Plasma

  • MOLECULAR BIOLOGY PROBLEMS OF DRUG DESIGN AND MECHANISM OF DRUG ACTION
  • Published:
Pharmaceutical Chemistry Journal Aims and scope

We present here our results from studies of the pharmacokinetic parameters of the original antituberculosis agent thiozonide, 100-mg capsules (ZAO Farm-Sintez, Moscow) using single increasing doses in different groups of healthy volunteers in a phase I clinical trial.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Tuberculosis in the Russian Federation. Basic Statistical Yearbook on Tuberculosis Used in the Russian Federation, Moscow (2011), p. 402.

  2. WHO Global Tuberculosis Control [in Russian], (2013); URL: http://www.who.int/tb/publications/global report/ru/

  3. M. I. Perel’man, Consilium Med., No. 12, 564 – 568 (2001).

  4. V. Yu. Mishin, Problemy Tuberkuleza, No. 7, 24 – 29 (2003).

  5. M. A. Karachunskii, Rus. Med. Zh., 9(21), 951 – 953 (2001).

    Google Scholar 

  6. V. I. Chukanov, Rus. Med. Zh., 9(21), 954 – 959 (2001).

    Google Scholar 

  7. Yu. M. Repin, Surgical Treatment [in Russian], Gippokrat, St. Petersburg (2007), p. 168.

  8. I. V. Bacharova, M. S. Burenkov, L. N. Lepekha, et al., Tuberkulez i Bolezni Legkikh, No. 6, 46 – 50 (2014).

  9. G. V. Ramenskaya, I. E. Shokhin, L. A. Men’shikova, et al., Khim.-Farm. Zh., 49(3), 46 – 49 (2015).

    Google Scholar 

  10. Federal Law No. 61-FZ “The Circulation of Medicines,” Adopted by resolution of the Government of the Russian Federation, April 12, 2010, Moscow (2010).

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to A. Yu. Savchenko.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 49, No. 3, pp. 3 – 6, March, 2015.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Savchenko, A.Y., Men’shikova, L.A., Ramenskaya, G.V. et al. Pharmacokinetic Studies of the Innovative Antituberculosis Drug Thiozonide in Plasma. Pharm Chem J 49, 147–150 (2015). https://doi.org/10.1007/s11094-015-1243-7

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11094-015-1243-7

Keywords

Navigation