Hydrolysis of bicaret was found to require stringent conditions – high temperature and a strongly acidic medium. These studies show that injection solutions of bicaret can be acidified.
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 48, No. 5, pp. 47 – 49, May, 2014.
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Berlyand, A.S., Prokopov, A.A. Studies of the Hydrolytic Stability of the Biologically Active Substance Bicaret. Pharm Chem J 48, 347–349 (2014). https://doi.org/10.1007/s11094-014-1108-5
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DOI: https://doi.org/10.1007/s11094-014-1108-5