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Applications of extraction freezing in pharmacology and biochemistry

  • Drug Synthesis Methods and Production Technologies
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Pharmaceutical Chemistry Journal Aims and scope

Abstract

A method for extracting organic substances from aqueous media by combining extraction with freezing is described. The method allows hydrophilic extractants to be used. Analysis of ionogenic organic compounds provides an example demonstrating the wide potential of this method. A method for the analysis of 1,4-benzodiazepines in urine was developed. As compared with existing methods, the sample preparation procedure described here is significantly quicker and simpler, and requires virtually no laboratory equipment.

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Authors and Affiliations

  1. Sochi State University of Tourism and Recreation, Sochi, Russia

    V. N. Bekhterev

  2. Forensic Medicine Bureau, Sochi, Russia

    S. N. Gavrilova

  3. Sochi Department, State Krasnodar Forensic Laboratory, Sochi, Russia

    E. V. Koshkareva

Authors
  1. V. N. Bekhterev
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  2. S. N. Gavrilova
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  3. E. V. Koshkareva
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Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 42, No. 2, pp. 44–46, February, 2008.

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Bekhterev, V.N., Gavrilova, S.N. & Koshkareva, E.V. Applications of extraction freezing in pharmacology and biochemistry. Pharm Chem J 42, 95–97 (2008). https://doi.org/10.1007/s11094-008-0067-0

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  • DOI: https://doi.org/10.1007/s11094-008-0067-0

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