Neuropsychology Review

, Volume 17, Issue 3, pp 239–257

Alcohol: Effects on Neurobehavioral Functions and the Brain

Authors

    • Departments of Anatomy and Neurobiology, Psychiatry, and NeurologyBoston University School of Medicine
    • Psychology Research ServiceVA Healthcare System
  • Ksenija Marinković
    • Radiology DepartmentHarvard Medical School
    • Athinoula A. Martinos Center for Biomedical ImagingMassachusetts General Hospital
Article

DOI: 10.1007/s11065-007-9038-6

Cite this article as:
Oscar-Berman, M. & Marinković, K. Neuropsychol Rev (2007) 17: 239. doi:10.1007/s11065-007-9038-6

Abstract

Alcoholism results from an interplay between genetic and environmental factors, and is linked to brain defects and associated cognitive, emotional, and behavioral impairments. A confluence of findings from neuroimaging, physiological, neuropathological, and neuropsychological studies of alcoholics indicate that the frontal lobes, limbic system, and cerebellum are particularly vulnerable to damage and dysfunction. An integrative approach employing a variety of neuroscientific technologies is essential for recognizing the interconnectivity of the different functional systems affected by alcoholism. In that way, relevant experimental techniques can be applied to assist in determining the degree to which abstinence and treatment contribute to the reversal of atrophy and dysfunction.

Keywords

AlcoholismFrontal lobesLimbic systemCerebellumRight hemisphere

Copyright information

© Springer Science+Business Media, LLC 2007