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Challenges in epilepsy-associated tumors

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References

  1. Luyken C, Blümcke I, Fimmers R, Urbach H, Elger CE, Wiestler OD, Schramm J (2003) The spectrum of long-term epilepsy-associated tumors: long-term seizure and tumor outcome and neurosurgical aspects. Epilepsia 44(6):822–830

    Article  PubMed  Google Scholar 

  2. Blümcke I, Spreafico R (2012) Cause matters: A neuropathological challenge to human epilepsies. Brain Pathol 22(3):347–349

    Article  PubMed  Google Scholar 

  3. Thom M, Blümcke I, Aronica E (2012) Long-term epilepsy-associated tumors. Brain Pathol 22:350–379

    Article  PubMed  Google Scholar 

  4. Giulioni M, Marucci G, Martinoni M, Volpi L, Riguzzi P, Marliani AF, Bisulli F, Tinuper P, Tassinari CA, Michelucci R, Rubboli G (2013) Seizure outcome in surgically treated drug-resistant mesial temporal lobe epilepsy based on the recent histopathological classifications. J Neurosurg 119(1):37–47. doi:10.3171/2013.3.JNS122132

    Article  PubMed  Google Scholar 

  5. Japp A, Gielen GH, Becker AJ (2013) Recent aspects of classification and epidemiology of epilepsy-associated tumors. Epilepsia 54:5–11

    Article  PubMed  Google Scholar 

  6. Cossu M, Fuschillo D, Bramerio M, Galli C, Gozzo F, Pelliccia V, Casaceli G, Tassi L, Lo Russo G (2013) Epilepsy surgery of focal cortical dysplasia-associated tumors. Epilepsia 54 (Suppl 9): 115–122. doi:10.1111/epi.12455

    Article  PubMed  Google Scholar 

  7. Englot DJ, Chang EF (2014) Rates and predictors of seizure freedom in resective epilepsy surgery: an update. Neurosurg Rev 37(3):389–404. doi:10.1007/s10143-014-0527-9 (discussion 404–405)

    Article  PubMed  Google Scholar 

  8. Blümcke I, Thom M, Aronica E, Armstrong DD, Vinters HV, Palmini A, Jacques TS, Avanzini G, Barkovich AJ, Battaglia G, Becker A, Cepeda C, Cendes F, Colombo N, Crino P, Cross JH, Delalande O, Dubeau F, Duncan J, Guerrini R, Kahane P, Mathern G, Najm I, Ozkara C, Raybaud, C, Represa A, Roper SN, Salamon N, Schulze-Bonhage A, Tassi L, Vezzani A, Spreafico R (2011) The clinicopathologic spectrum of focal cortical dysplasias: a consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission. Epilepsia 52: 158–174. doi:10.1111/j.1528

    Article  PubMed  Google Scholar 

  9. Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW (2016) The 2016 world health organization classification of tumors of the central nervous system: a summary. Acta Neuropathol. doi:10.1007/s00401-016-1545-1

    Google Scholar 

  10. Prayson RA, Napekoski KM (2012) Composite ganglioglioma/dysembryoplastic neuroepithelial tumor: a clinicopathologic study of 8 cases. Hum Pathol 43:1113–1118

    Article  PubMed  Google Scholar 

  11. Marucci G, de Biase D, VisaniM, GiulioniM, MartinoniM, Volpi L, Riguzzi P, Rubboli G, Michelucci R, Tallini G (2014) Mutant BRAF in low grade epilepsy-associated tumors and focal cortical dysplasia. Ann Clin Transl Neurol 1(2):130–134. doi:10.1002/acn3.31

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  12. Cancer Genome Atlas Research Network (2015) Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. N Engl J Med 372:2481–2498

    Article  Google Scholar 

  13. Liu J, Reeves C, Michalak Z, Coppola A, Diehl B, Sisodiya SM, Thom M (2014) Evidence for mTOR pathway activation in a spectrum of epilepsy-associated pathologies. Acta Neuropathol Commun 8(2):71. doi:10.1186/2051-5960-2-71

    Article  Google Scholar 

  14. Lim JS, Kim WI, Kang HC, Kim SH, Park AH, Park EK, Cho YW, Kim S, Kim HM, Kim JA, Kim J, Rhee H, Kang SG, Kim HD, Kim D, Kim DS, Lee JH (2015) Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy. Nat Med 21:395–400

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. IRCCS - Institute of Neurological Sciences of Bologna, Bellaria Hospital, Via Altura 1/8, 40139, Bologna, Italy

    Marco Giulioni, Matteo Martinoni & Gianluca Marucci

Authors
  1. Marco Giulioni
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  2. Matteo Martinoni
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  3. Gianluca Marucci
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Corresponding author

Correspondence to Marco Giulioni.

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None of the authors has any conflict of interest to disclose.

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Giulioni, M., Martinoni, M. & Marucci, G. Challenges in epilepsy-associated tumors. J Neurooncol 130, 239–240 (2016). https://doi.org/10.1007/s11060-016-2230-x

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  • DOI: https://doi.org/10.1007/s11060-016-2230-x

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