References
Khoury O, Ghazale N, Stone E, El-Sibai M, Frankel AE, Abi-Habib RJ (2015) Human recombinant arginase I (Co)-PEG5000 [HuArgI (Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human glioblastoma cells. J Neurooncol 122(1):75–85. doi:10.1007/s11060-014-1698-5
Lam TL, Wong GK, Chong HC, Cheng PN, Choi SC, Chow TL, Kwok SY, Poon RT, Wheatley DN, Lo WH, Leung YC (2009) Recombinant human arginase inhibits proliferation of human hepatocellular carcinoma by inducing cell cycle arrest. Cancer Lett 277(1):91–100. doi:10.1016/j.canlet.2008.11.031
Fiedler T, Strauss M, Hering S, Redanz U, William D, Rosche Y, Classen CF, Kreikemeyer B, Linnebacher M, Maletzki C (2015) Arginine deprivation by arginine deiminase of Streptococcus pyogenes controls primary glioblastoma growth in vitro and in vivo. Cancer Biol Ther 16(7):1047–1055. doi:10.1080/15384047.2015.1026478
Acknowledgments
We would like to acknowledge Dr. Aden Ka Yin Chan and Prof. Ho Keung Ng for providing us GBM patients samples (Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong), and also Dr. Kin Pong U and Dr. Paul Ning Man Cheng (BCT International Ltd., Hong Kong) for providing us the compound, PEG-BCT-100.
Author information
Authors and Affiliations
Corresponding authors
Rights and permissions
About this article
Cite this article
Choy, C.T., Wong, C.H. & Loong, H.H.F. Low expressions of ASS1 and OTC in glioblastoma suggest the potential clinical use of recombinant human arginase (rhArg). J Neurooncol 129, 579–581 (2016). https://doi.org/10.1007/s11060-016-2209-7
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11060-016-2209-7