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Informational Aspects of the State of the Microcirculation after Surgical Sympathectomy in Post-Traumatic Complex Regional Pain Syndrome

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The informational aspects of tissue microcirculation after sympathectomy were studied in 64 patients with complex regional pain syndrome using wavelet analysis of oscillations in blood flow in the microcirculatory bed of the skin. Early rearrangements of information in the trophotropic direction at the tissue level and the domination and preservation of this information throughout the microcirculatory network supports the optimal execution of adaptive reactions and, as a result, maximal treatment efficacy. In these cases, complete elimination of disease can be attained, with positive outcomes. Maximum therapeutic efficacy could not be obtained without early informational changes. Conversely, the dominance and preservation of ergotropic information in the early post-operative period constituted an unfavorable prognostic factor for the clinical outcome of sympathectomy. The formation of information exchange in the trophotropic direction in microvascular networks does not require tissue desympathization; achievement of a certain threshold level of decreased sympathetic activity is sufficient.

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Authors and Affiliations

  1. Central Research Institute of Traumatology and Orthopedics, Russian Ministry of Health, Moscow, Russia

    A. I. Krupatkin

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  1. A. I. Krupatkin
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Correspondence to A. I. Krupatkin.

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Translated from Zhurnal Nevrologii i Psikhiatrii imeni S. S. Korsakova, Vol. 113, No. 6, Iss. I, pp. 17–21, June, 2013.

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Krupatkin, A.I. Informational Aspects of the State of the Microcirculation after Surgical Sympathectomy in Post-Traumatic Complex Regional Pain Syndrome. Neurosci Behav Physi 44, 1059–1063 (2014). https://doi.org/10.1007/s11055-014-0024-1

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