Neuroscience and Behavioral Physiology

, Volume 37, Issue 5, pp 523–526

Efficacy of neuroprotectors in patients with tension headaches

  • L. A. Medvedeva
  • A. V. Gnezdilov
  • O. I. Zagorul’ko
  • A. V. Syrovegin
  • N. V. Samoilova
Article

DOI: 10.1007/s11055-007-0046-z

Cite this article as:
Medvedeva, L.A., Gnezdilov, A.V., Zagorul’ko, O.I. et al. Neurosci Behav Physiol (2007) 37: 523. doi:10.1007/s11055-007-0046-z

Abstract

Studies were performed on 126 patients with chronic tension headache (CTH). Patients were divided into two groups — an experimental group (64 patients) and a control group (62). Control patients received standard treatment (tizanidine, fluoxetine, vinpocetin, and manual acupressure of active points in the trapezius muscles and the temporomastoid area of the head); the experimental group also received Mexidol. Clinical and neurophysiological studies, including electromyography, were performed before and after treatment. Comparison of the treatment outcomes in the two groups showed that inclusion of Mexidol into the complex therapy of chronic CTH led to faster and more marked clinical effects.

Key words

chronic tension headacheelectroneuromyographytreatmentMexidol

Copyright information

© Springer Science+Business Media, Inc. 2007

Authors and Affiliations

  • L. A. Medvedeva
    • 1
  • A. V. Gnezdilov
    • 1
  • O. I. Zagorul’ko
    • 1
  • A. V. Syrovegin
    • 1
  • N. V. Samoilova
    • 1
  1. 1.Russian Scientific Center for SurgeryRussian Academy of Medical SciencesMoscow