Research paper

Journal of Nanoparticle Research

, Volume 11, Issue 3, pp 623-633

Gold and gold–silver core-shell nanoparticle constructs with defined size based on DNA hybridization

  • Andrea SteinbrückAffiliated withNanobiophotonics Department, Institute of Photonic Technology Email author 
  • , Andrea CsakiAffiliated withNanobiophotonics Department, Institute of Photonic Technology
  • , Kathrin RitterAffiliated withDepartment of Physical Chemistry and Microreaction Technology, Technical University Ilmenau, Institute for Micro and Nanotechnology
  • , Martin LeichAffiliated withDepartment of Physical Chemistry and Microreaction Technology, Technical University Ilmenau, Institute for Micro and Nanotechnology
  • , J. Michael  KöhlerAffiliated withDepartment of Physical Chemistry and Microreaction Technology, Technical University Ilmenau, Institute for Micro and Nanotechnology
  • , Wolfgang FritzscheAffiliated withNanobiophotonics Department, Institute of Photonic Technology

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Abstract

Nanoparticles represent versatile building blocks in material science and nanotechnology. Thereby, the defined assembly of nanostructures (13 and 56 nm in diameter, respectively) is of significant importance. Short DNA sequences can be bound to the nanoparticle surface thus enabling highly specific DNA hybridization-driven events that direct the formation of nanoparticle constructs.

In this paper, examples for the defined formation of gold nanoparticle constructs are demonstrated. In addition, gold–silver core-shell nanoparticles are introduced as further building blocks for the hybridization-controlled formation of nanoparticle constructs.

Keywords

Gold Silver Nanoparticle Core-shell DNA Hybridization TEM UV–Vis spectroscopy Guided assembling Nanostructure