Perspectives

Journal of Nanoparticle Research

, Volume 10, Issue 8, pp 1231-1240

Open Access This content is freely available online to anyone, anywhere at any time.

Hybrid approaches to nanometer-scale patterning: Exploiting tailored intermolecular interactions

  • Thomas J. MullenAffiliated withDepartments of Chemistry and Physics, The Pennsylvania State University
  • , Charan SrinivasanAffiliated withDepartment of Engineering Science and Mechanics, The Pennsylvania State University
  • , Mitchell J. ShusterAffiliated withDepartments of Chemistry and Physics, The Pennsylvania State University
  • , Mark W. HornAffiliated withDepartment of Engineering Science and Mechanics, The Pennsylvania State University
  • , Anne M. AndrewsAffiliated withDepartment of Veterinary and Biomedical Science and Huck Institutes of the Life Sciences, The Pennsylvania State University Email author 
  • , Paul S. WeissAffiliated withDepartments of Chemistry and Physics, The Pennsylvania State University Email author 

Abstract

In this perspective, we explore hybrid approaches to nanometer-scale patterning, where the precision of molecular self-assembly is combined with the sophistication and fidelity of lithography. Two areas––improving existing lithographic techniques through self-assembly and fabricating chemically patterned surfaces––will be discussed in terms of their advantages, limitations, applications, and future outlook. The creation of such chemical patterns enables new capabilities, including the assembly of biospecific surfaces to be recognized by, and to capture analytes from, complex mixtures. Finally, we speculate on the potential impact and upcoming challenges of these hybrid strategies.

Keywords

Self-assembly Nanolithography Chemical patterning Soft lithography Intermolecular interactions Future science challenges