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Acne-Like Subcutaneous Phaeohyphomycosis Caused by Cladosporium cladosporioides: A Rare Case Report and Review of Published Literatures

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Abstract

We report a rare case of subcutaneous phaeohyphomycosis caused by Cladosporium cladosporioides. A 21-year-old man was presented to our clinic with the history of cysts and nodules on his face and neck for 5 years. He was diagnosed subcutaneous phaeohyphomycosis according to the finding of fungal elements in histopathological examination and direct microscopic examination of cyst pus, which was confirmed by positive culture of the cyst pus. The isolate grown on culture was identified as C. cladosporioides on the basis of morphological characters and sequence of the ITS region of ribosomal DNA. After treatment with oral itraconazole, he almost completely resolved the inflammatory lesions. To the best of our knowledge, this is the first case report of C. cladosporioides infection presented with multiple cysts and nodules like acne.

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References

  1. Li DM, de Hoog GS. Cerebral phaeohyphomycosis: a cure at what lengths? Lancet Infect Dis. 2009;9:376–83.

    Article  PubMed  Google Scholar 

  2. Kwon-Chung KJ, Schwartz IS, Rybak BJ. A pulmonary fungus ball produced by Cladosporium cladosporioides. Am J Clin Pathol. 1975;64:564–8.

    Article  CAS  PubMed  Google Scholar 

  3. Polack FM, Siverio C, Bresky RH. Corneal chromomycosis: double infection by Phialophora verrucosa (Medlar) and Cladosporium cladosporioides (Frescenius). Ann Ophthalmol. 1976;8:139–44.

    CAS  PubMed  Google Scholar 

  4. Gugnani HC, Gupta S, Talwar RS. Role of opportunistic fungi in ocular infections in Nigeria. Mycopathologia. 1978;65:155–66.

    Article  CAS  PubMed  Google Scholar 

  5. Drabick JJ, Gomatos PJ, Solis JB. Cutaneous cladosporiosis as a complication of skin testing in a man positive for human immunodeficiency virus. J Am Acad Dermatol. 1990;22:135–6.

    Article  CAS  PubMed  Google Scholar 

  6. Annessi G, Cimitan A, Zambruno G, Di Silverio A. Cutaneous phaeohyphomycosis due to Cladosporium cladosporioides. Mycoses. 1992;35:243–6.

    Article  CAS  PubMed  Google Scholar 

  7. Pereiro M Jr, Jo-Chu J, Toribio J. Phaeohyphomycotic cyst due to Cladosporium cladosporioides. Dermatology. 1998;197:90–2.

    PubMed  Google Scholar 

  8. Gugnani HC, Sood N, Singh B, Makkar R. Case report. Subcutaneous phaeohyphomycosis due to Cladosporium cladosporioides. Mycoses. 2000;43:85–7.

    Article  CAS  PubMed  Google Scholar 

  9. Vieira MR, Milheiro A, Pacheco FA. Phaeohyphomycosis due to Cladosporium cladosporioides. Med Mycol. 2001;39:135–7.

    Article  CAS  PubMed  Google Scholar 

  10. Kantarcioglu AS, Yücel A, de Hoog GS. Case report. Isolation of Cladosporium cladosporioides from cerebrospinal fluid. Mycoses. 2002;45:500–3.

    CAS  PubMed  Google Scholar 

  11. Huang WM, Li W, Guo HW, Luo YC, Chen QX. A case of cutaneous phaeohyphomycosis due to Cladosporium cladosporioides [in Chinese]. Chin J Mycol. 2008;3:157–60.

    Google Scholar 

  12. Chew FL, Subrayan V, Chong PP, Goh MC, Ng KP. Cladosporium cladosporioides keratomycosis: a case report. Jpn J Ophthalmol. 2009;53:657–9.

    Article  PubMed  Google Scholar 

  13. Yu J, Wan Z, Lu QY, Chen W, Wang XH. Onychomycosis caused by Trichophyton rubrum and Cladosporium cladosporioides in psoriasis patient: one case report [in Chinese]. Chin J Mycol. 2009;4:298–300.

    Google Scholar 

  14. Duquia RP, de Almeida HL, Jr Vettorato G, Rocha NM, de Castro LA. Ecthyma-like phaeohyphomycosis caused by Cladosporium cladosporioides. Mycoses. 2010;53:541–3.

    Article  PubMed  Google Scholar 

  15. Sang H, Zheng XE, Zhou WQ, He W, Lv GX, Shen YN, et al. A case of subcutaneous phaeohyphomycosis caused by Cladosporium cladosporioides and its treatment. Mycoses. 2012;55:195–7.

    CAS  PubMed  Google Scholar 

  16. Giri S, Kindo AJ, Rao S, Kumar AR. Unusual causes of fungal rhinosinusitis: a study from a tertiary care centre in South India. Indian J Med Microbiol. 2013;31:379–84.

    Article  CAS  PubMed  Google Scholar 

  17. Zeller S, Lempert S, Goebeler M, Hamm H, Kolb-Mäurer A. Cladosporium cladosporioides: a so far unidentified cause of white piedra. Mycoses. 2015;58:315–7.

    Article  CAS  PubMed  Google Scholar 

  18. Bordoloi P, Nath R, Borgohain M, Huda MM, Barua S, Dutta D, et al. Subcutaneous mycoses: an aetiological study of 15 cases in a tertiary care hospital at Dibrugarh, Assam, northeast India. Mycopathologia. 2015;179:425–35.

    Article  PubMed  Google Scholar 

  19. Nath R, Barua S, Barman J, Swargiary P, Borgohain M, et al. Subcutaneous Mycosis due to Cladosporium cladosporioides and Bipolaris cynodontis from Assam, North-East India and review of published. Mycopathologia. 2015;180:379–87.

    Article  PubMed  Google Scholar 

  20. Zhou YB, Chen P, Sun TT, Wang XJ, Li DM. Acne-like subcutaneous phaeohyphomycosis caused by Cladosporium cladosporioides: a rare case report and review of published literatures. Mycopathologia. 2016. doi:10.1007/s11046-016-9995-5.

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Acknowledgments

We thank the patient for providing permission to share his information. This work is supported by Project 81571967 of National Natural Science Foundation of China.

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Authors and Affiliations

  1. Department of Dermatology, Peking University Third Hospital, No. 49 North Garden Road, Haidian District, Beijing, 100191, China

    Ya Bin Zhou, Ping Chen, Ting Ting Sun, Xing Jia Wang & Dong Ming Li

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  1. Ya Bin Zhou
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  2. Ping Chen
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  3. Ting Ting Sun
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  4. Xing Jia Wang
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  5. Dong Ming Li
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Correspondence to Dong Ming Li.

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Zhou, Y.B., Chen, P., Sun, T.T. et al. Acne-Like Subcutaneous Phaeohyphomycosis Caused by Cladosporium cladosporioides: A Rare Case Report and Review of Published Literatures. Mycopathologia 181, 567–573 (2016). https://doi.org/10.1007/s11046-016-9995-5

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  • DOI: https://doi.org/10.1007/s11046-016-9995-5

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