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Genetic Predictors of Susceptibility to Dermatophytoses

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Abstract

Countless observational studies conducted over the last century reveal that dermatophytes infect humans of every age, race, gender, and socioeconomic status with strikingly high rates. The curious disparity in dermatophyte infection patterns observed within and between populations has led countless investigators to explore whether genetics underlie a susceptibility to, or confer protection against, dermatophyte infections. This paper examines the data that offer a link between genetics and dermatophytoses and discusses the underlying mechanisms that support these observations.

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Authors and Affiliations

  1. UMKC School of Medicine, Kansas City, MO, USA

    Susan M. Abdel-Rahman

  2. Section of Therapeutic Innovation, Children’s Mercy Hospital, Kansas City, MO, USA

    Susan M. Abdel-Rahman

  3. Division of Pediatric Clinical Pharmacology, Toxicology, and Therapeutic Innovation, Children’s Mercy Hospitals and Clinics, 2401 Gillham Rd., Kansas City, MO, 64108, USA

    Susan M. Abdel-Rahman

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Abdel-Rahman, S.M. Genetic Predictors of Susceptibility to Dermatophytoses. Mycopathologia 182, 67–76 (2017). https://doi.org/10.1007/s11046-016-0046-z

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