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A 9-Month-Old Girl from Iran with Extensive Erythematous Plaques Due to Trichophyton simii, a Zoophilic Dermatophyte

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Abstract

The incidence of dermatophytosis due to Trichophyton simii is generally considered to be limited to endemic areas, particularly one area of India. However, the high similarity between the morphological features of atypical T. simii isolates and those of other dermatophytes such as Trichophyton interdigitale and Arthroderma benhamiae may lead to misidentification of the cause of dermatophytosis in many instances. We investigated a rare case of tinea corporis in a 9-month-old female with extensive erythematous lesions. Morphological features of the recovered isolate from the culture resulted in the identification of Trichophyton interdigitale. For accurate identification, the internal transcribed spacer regions (ITS1 and ITS2) of the ribosomal DNA (rDNA) gene were sequenced and the isolate was ultimately identified as T. simii. In conclusion, T. simii, which has been formerly known to be restricted to specific endemic regions, appears to be not infrequent in non-endemic areas but instead simply less well-known and consequently underestimated. To determine its actual prevalence of infection, the application of DNA-based molecular methodologies is required.

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Authors and Affiliations

  1. Invasive Fungi Research Center (IFRC)/Department of Medical Mycology and Parasitology, School of Medicine, Mazandaran University of Medical Sciences, Km 18 Khazarabad Road, P.O. Box 48175-1665, Sari, Iran

    Saham Ansari, Mohammad T. Hedayati & Seyedmojtaba Seyedmousavi

  2. Department of Medical Parasitology and Mycology, School of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran

    Sadegh Nouripour-Sisakht, Haniyeh Mohammadi & Yousef Fazli

  3. Department of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

    Ali Rezaei-Matehkolaei

  4. Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

    Ali Rezaei-Matehkolaei

  5. Department of Medical Pathology, School of Medicine, Yasuj University of Medical Sciences, Yasuj, Iran

    Ramin Jannesar

  6. Division of Mycology, Department of Microbiology, Faculty of Medicine, University of Çukurova, Adana, Turkey

    Macit Ilkit

  7. Department of Medical Microbiology and Infectious Diseases, Erasmus MC, Rotterdam, The Netherlands

    Seyedmojtaba Seyedmousavi

  8. Department of Medical Microbiology, Radboud UMC, Nijmegen, The Netherlands

    Seyedmojtaba Seyedmousavi

Authors
  1. Saham Ansari
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  2. Mohammad T. Hedayati
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  3. Sadegh Nouripour-Sisakht
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  4. Ali Rezaei-Matehkolaei
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  5. Ramin Jannesar
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  6. Haniyeh Mohammadi
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  7. Yousef Fazli
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  8. Macit Ilkit
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  9. Seyedmojtaba Seyedmousavi
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Corresponding author

Correspondence to Mohammad T. Hedayati.

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Conflict of interest

Seyedmojtaba Seyedmousavi has received research and travel grants from Astellas Pharma B.V. and a travel grant from Gilead Sciences. All of the other authors have no competing interests. The authors alone are responsible for the content and composition of the manuscript.

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Ansari, S., Hedayati, M.T., Nouripour-Sisakht, S. et al. A 9-Month-Old Girl from Iran with Extensive Erythematous Plaques Due to Trichophyton simii, a Zoophilic Dermatophyte. Mycopathologia 181, 451–455 (2016). https://doi.org/10.1007/s11046-015-9981-3

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  • DOI: https://doi.org/10.1007/s11046-015-9981-3

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