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Early Diagnosis of Cutaneous Mucormycosis Due to Lichtheimia corymbifera After a Traffic Accident

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Abstract

A case report of cutaneous mucormycosis and obstacles to early diagnosis is presented. A 38-year-old male was involved in a car accident that led to amputation of both lower limbs. Subsequently, he developed fungal wound infection of the left lower limb stump. The infection was detected very early, although the diagnosis was difficult because only a small area was affected and histopathological examination was initially negative. The infection was proven by microscopy, culture and histopathology. The isolate was identified by sequencing of the rDNA ITS region gene (internal transcribed spacer region of ribosomal DNA) as Lichtheimia corymbifera. Liposomal amphotericin B and surgery were successful in management of the disease.

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Acknowledgments

This work was supported by the Palacky University Olomouc Internal Grant Agency (project no. IGA_LF_2015_035), the Ministry of Education, Youth and Sports of the Czech Republic (SVV project), and the project “BIOCEV—Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University” (CZ.1.05/1.1.00/02.0109) from the European Regional Development Fund.

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Correspondence to Pavlina Lyskova.

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Tyll, T., Lyskova, P., Hubka, V. et al. Early Diagnosis of Cutaneous Mucormycosis Due to Lichtheimia corymbifera After a Traffic Accident. Mycopathologia 181, 119–124 (2016). https://doi.org/10.1007/s11046-015-9943-9

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  • DOI: https://doi.org/10.1007/s11046-015-9943-9

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