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Paracoccidioidomycosis Mimicking Sarcoidosis: A Review of 8 Cases

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Abstract

Sarcoidosis is a multisystem disorder that is characterized by noncaseous epithelioid cell granulomas, which may affect almost any organ. Thoracic involvement is common and accounts for most of the morbidity and mortality associated with this disease. The diagnosis is based on exhaustive exclusion of differential diagnoses, particularly granulomatous infections. We report data on eight patients with paracoccidioidomycosis mimicking sarcoidosis. Five patients presented with a chronic pulmonary type infection and three had a disseminated form after immunosuppressive treatment. The mycological diagnosis in noncaseating granulomas is emphasized and reviewed.

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Authors and Affiliations

  1. Programa de Pós-Graduação em Ciências Pneumológicas, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil

    Mariana Guimarães Coelho

  2. Laboratório de Micologia, Hospital Santa Rita, Irmandade Santa Casa de Misericórdia Porto Alegre (ISCMPA), Annes Dias 285, Porto Alegre, RS, 90020-090, Brazil

    Cecília Bittencourt Severo, Flávio de Mattos Oliveira & Luiz Carlos Severo

  3. Universidade Federal de Ciências da Saúde de Porto Alegre, UFCSPA, Porto Alegre, Brazil

    Cecília Bittencourt Severo

  4. Serviço de Radiologia, ISCMPA, Porto Alegre, RS, Brazil

    Bruno Hochhegger

  5. Pós-Graduação em Ciências Pneumológicas, UFRGS, Pesquisador 1B CNPq, Porto Alegre, Brazil

    Luiz Carlos Severo

Authors
  1. Mariana Guimarães Coelho
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  2. Cecília Bittencourt Severo
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  3. Flávio de Mattos Oliveira
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  4. Bruno Hochhegger
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  5. Luiz Carlos Severo
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Corresponding author

Correspondence to Luiz Carlos Severo.

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Coelho, M.G., Severo, C.B., de Mattos Oliveira, F. et al. Paracoccidioidomycosis Mimicking Sarcoidosis: A Review of 8 Cases. Mycopathologia 181, 137–143 (2016). https://doi.org/10.1007/s11046-015-9938-6

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  • DOI: https://doi.org/10.1007/s11046-015-9938-6

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