Article

Mycopathologia

, Volume 174, Issue 1, pp 87-92

Cryptococcus gattii Infection in an Immunocompetent Patient from Southern Italy

  • Roberta IattaAffiliated withDepartment of Biomedical Science and Human Oncology, Section of Hygiene, “Aldo Moro” University of Bari Email author 
  • , Ferry HagenAffiliated withDepartment of Yeast and Basidiomycete Research, CBS-KNAW Fungal Biodiversity CentreCanisius Wilhelmina Hospital
  • , Cecilia FicoAffiliated withDepartment of Infectious Disease, Triggiano Hospital
  • , Nunzia LopatrielloAffiliated withLaboratory of Clinical Pathology, Triggiano Hospital
  • , Teun BoekhoutAffiliated withDepartment of Yeast and Basidiomycete Research, CBS-KNAW Fungal Biodiversity Centre
  • , Maria Teresa MontagnaAffiliated withDepartment of Biomedical Science and Human Oncology, Section of Hygiene, “Aldo Moro” University of Bari

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Abstract

Cryptococcus gattii has becoming more prevalent in temperate climate zones, during the past decades. We describe a C. gattii serotype B infection in an immunocompetent Italian patient with sclerosing cholangitis. The patient traveled once to Eastern Canada and otherwise no other countries than Italy were visited. Molecular analysis revealed that the C. gattii isolate belong to genotype AFLP4/VGI and has mating-type α which is the most common genotype in the Mediterranean environment. The C. gattii strain was found to be closely related, but not identical, to other C. gattii strains from the Mediterranean area.

Keywords

Cryptococcus gattii Cryptococcosis Molecular type Italy Infection