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Recent developments in utility of green multi-component reactions for the efficient synthesis of polysubstituted pyrans, thiopyrans, pyridines, and pyrazoles

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Abstract

Developments made since 2010 in the utilization of multi-component reactions as green efficient methodologies for the synthesis of polysubstituted pyrans, thiopyrans, pyridines, and pyrazoles are reviewed and the mechanisms of these processes are discussed. Reference is made to classical older synthetic methods developed earlier in our laboratories.

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Acknowledgments

The authors are grateful to Kuwait University Research Administration for financial support of project SC12/13.

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  1. Chemistry Department, Faculty of Science, Kuwait University, P.O. Box 5969, 13060, Safat, Kuwait

    Mohamed Hilmy Elnagdi, Moustafa Sherief Moustafa & Saleh Mohammed Al-Mousawi

  2. Department of Chemistry, Faculty of Science for Girls, King Abdulaziz University, Jeddah, 21533, Kingdom of Saudi Arabia

    Ramadan Ahmed Mekheimer

  3. Chemistry Department, Faculty of Science, Minia University, Minia, 61519, AR Egypt

    Ramadan Ahmed Mekheimer & Kamal Usef Sadek

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  1. Mohamed Hilmy Elnagdi
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Elnagdi, M.H., Moustafa, M.S., Al-Mousawi, S.M. et al. Recent developments in utility of green multi-component reactions for the efficient synthesis of polysubstituted pyrans, thiopyrans, pyridines, and pyrazoles. Mol Divers 19, 625–651 (2015). https://doi.org/10.1007/s11030-015-9594-2

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