Molecular Diversity

, Volume 15, Issue 3, pp 613–630

The flow synthesis of heterocycles for natural product and medicinal chemistry applications

  • Marcus Baumann
  • Ian R. Baxendale
  • Steven V. Ley
Full-Length Paper

DOI: 10.1007/s11030-010-9282-1

Cite this article as:
Baumann, M., Baxendale, I.R. & Ley, S.V. Mol Divers (2011) 15: 613. doi:10.1007/s11030-010-9282-1

Abstract

This article represents an overview of recent research from the Innovative Technology Centre in the field of flow chemistry which was presented at the FROST2 meeting in Budapest in October 2009. After a short introduction of this rapidly expanding field, we discuss some of our results with a main focus on the synthesis of heterocyclic compounds which we use in various natural product and medicinal chemistry programmes.

Keywords

Flow synthesis Micro-reactor Meso-reactor Solid-supported reagents Heterocycles Automated synthesis 

Copyright information

© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  • Marcus Baumann
    • 1
  • Ian R. Baxendale
    • 1
  • Steven V. Ley
    • 1
  1. 1.Innovative Technology Centre for Advanced Chemical Synthesis, Department of ChemistryUniversity of CambridgeCambridgeUnited Kingdom

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