Studies of human blood are carried out for numerous parameters. One of them is sodium concentration. In this article, ion chromatographic, spectrophotometric, titrimetric, and gravimetric procedures for determination of sodium concentration in plasma, serum, and whole blood are described. Brief data on these procedures and results of their comparative tests are presented.
Similar content being viewed by others
References
C. Anderson, “Ion chromatography: A new technique for clinical chemistry,” Clin. Chem., 22, No. 9, 1424–1426 (1976).
H. Shintani, “Cation content of serum as determined by ion chromatography and with ion-selective electrodes,” Clin. Chem., 32, No. 2, 406–407 (1986).
P. Hajós, A. Kener, and M. Horvath, “Comparative measurements for determination of alkali ions in human blood serum by ion-chromatography,” Clin. Chem., 33, No. 4, 617–618 (1987).
P. Oesper and C. J. Pauerstein, “A volumetric method for serum sodium,” Clin. Chem., 5, No. 6, 551–556 (1959).
E. K. Kim, L. D. Waddell, and J. E. Logan, “Evaluation for four reagent kits and two flame photometers used to determine sodium and potassium in serum,” Clin. Chem., 18, No. 2, 124–128 (1972).
A. Kumar, E. Chapoteau, B. P. Czech, et al., “Chromogenic ionophore-based methods for spectrophotometric assay of sodium and potassium in serum and plasma,” Clin. Chem., 34, No. 9, 1709–1712 (1988).
K. Seiler, K. Wang, E. Bakker, et al., “Characterization of sodium-selective optode membranes based on neutral ionophores and assay of sodium in plasma,” Clin. Chem., 37, No. 8, 1350–1355 (1991).
M. N. Berry, R. D. Mazzachi, M. Pejakovic, and M. J. Peake, “Enzymatic determination of sodium in serum,” Clin. Chem., 34, No. 11, 2295–2298 (1988).
R. Quiles, J. M. Fernández-Romero, E. Fernández, et al., “Automated enzymatic determination of sodium in serum,” Clin. Chem., 39, No. 3, 500–503 (1993).
G. Steen, B. Van Leeuwen, P. Langesla, and J. J. Van der Reijden, “Selectivity of enzymatic assays of sodium and potassium,” Clin. Chem., 40, No. 4, 671 (1994).
J. Van Pelt, “Enzymatic determinations of sodium, potassium, and chloride in serum compared with determinations by flame photometry, coulometry, and ion-selective electrodes,” Clin. Chem., 40, No. 5, 846–847 (1994).
W. Hübl, R. Wejbora, I. Shafti-Keramat, et al., “Enzymatic determination of sodium, potassium, and chloride in abnormal (hemolyzed, icteric, lipemic, paraproteinemic, or uremic) serum samples,” Clin. Chem., 40, No. 8, 1528–1531 (1994).
H. Dahms, “Automated potentiometric determination of inorganic blood constituents (Na+, K+, H+, Cl–),” Clin. Chem., 13, No. 6, 437–450 (1967).
R. Schaffer, R. A. Velapoldi, R. C. Paule, et al., “A multilaboratory-evaluated reference method for the determination of serum sodium,” Clin. Chem., 27, No. 11, 1824–1828 (1981).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Izmeritel’naya Tekhnika, No. 6, pp. 68–72, June, 2016.
Rights and permissions
About this article
Cite this article
Buzanovskii, V.A. Ion Chromatography, Spectrophotometry, Titrimetry, and Gravimetry Measurements of Sodium Concentration in the Blood. Meas Tech 59, 678–683 (2016). https://doi.org/10.1007/s11018-016-1029-7
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11018-016-1029-7