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Dose verification of volumetric modulation arc therapy by using a NIPAM gel dosimeter combined with a parallel-beam optical computed tomography scanner

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Abstract

Volumetric modulated arc therapy (VMAT) was developed to shorten treatment time and increase target conformance. However, a true three-dimensional (3D) gel dosimeter is needed for dose verification. In this study, two clinic cases were adopted: a simple case of lung cancer and a complex case of larynx cancer. For each clinic case, two treatment plans were generated for the same planning target volume using VMAT and intensity modulated radiation therapy calculation software packages. An N-isopropylacrylamide (NIPAM) polymer gel dosimeter was used for 3D dose verification. In addition, the dose characteristics of the NIPAM gel dosimeter were investigated for the two clinic cases.

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References

  1. Back SAJ (2009) Clinical applications of gel dosimeters. J Phys Conf Ser 164:012049

    Article  Google Scholar 

  2. Baldock C, De Deene Y, Doran S, Ibbott G, Jirasek A, Lepage M, McAuley KB, Oldham M, Schreine LJ (2010) Polymer gel dosimetry. Phys Med Biol 55:R1–R63

    Article  CAS  Google Scholar 

  3. Gore JC, Ranade M, Maryanski MJ, Schulz RJ (1996) Radiation dose distributions in three dimensions from tomographic optical density scanning of polymer gels: I. Development of an optical scanner. Phys Med Biol 41:2695–2704

    Article  CAS  Google Scholar 

  4. De Deene Y, Hanselaer P, De Wagter C, Achten E, De Neve W (2000) An investigation of the chemical stability of a monomer/polymer gel dosimeter. Phys Med Biol 45:859–878

    Article  Google Scholar 

  5. Chang YJ, Chen CH, Hsieh BT (2014) Characterization of long-term dose stability of N-isopropylacrylamide polymer gel dosimetry. J Radioannal Nucl Chem 301:765–780

    Article  CAS  Google Scholar 

  6. Krstajic N, Doran SJ (2006) Focusing optics of a parallel beam CCD optical tomography apparatus for 3D radiation gel dosimetry. Phys Med Biol 51:2055–2075

    Article  Google Scholar 

  7. Chang YJ (2015) Use of a speckle reduction technique to improve the reconstruction image quality of CCD-based optical computed tomography scanner. Nucl Instrum Methods Phys Res Sect A 784:585–589

    Article  CAS  Google Scholar 

  8. Huang WT, Chen CH, Hung CN, Tuan CC, Chang YJ (2015) Implementation of a parallel-beam optical-CT apparatus for three-dimensional radiation dosimetry using a high-resolution CCD camera. Nucl Instrum Methods Phys Res Sect A 784:590–596

    Article  CAS  Google Scholar 

  9. Wuu CS, Xu Y (2006) Three-dimensional dose verification for intensity modulated radiation therapy using optical CT based polymer gel dosimetry. Med Phys 33:1412–1419

    Article  Google Scholar 

  10. Chang YJ, Hsieh BT, Liang JA (2011) A systematic approach to determine optimal composition of gel used in radiation therapy. Nucl Instrum Methods Phys Res Sect A 652:783–785

    Article  CAS  Google Scholar 

  11. Hsieh BT, Chang YJ, Han RP, Wu J, Hsieh LL, Chang CJ (2011) A study on dose response of NIPAM-based dosimeter used in radiotherapy. J Radioanal Nucl Chem 290:141–148

    Article  CAS  Google Scholar 

  12. Chang YJ, Hsieh BT (2012) Effect of composition interactions on the dose response of an N-isopropylacrylamide gel dosimeter. PLoS ONE 7:1–8

    Article  Google Scholar 

  13. De Deene Y, Pittomvils G, Visalatchi S (2007) The influence of cooling rate on the accuracy of normoxic polymer gel dosimeters. Phys Med Biol 52:2719–2728

    Article  Google Scholar 

  14. Hsieh BT, Wu J, Chang YJ (2013) Verification on dose profile variation of 3D polymer gel dosimeter. IEEE Trans Nucl Sci 60:560–565

    Article  CAS  Google Scholar 

  15. Elekta VMAT. https://www.elekta.com/radiotherapy/treatment-solutions/elekta-vmat.html. Accessed 10 Jun 2016

  16. Ceberg S, Gagne I, Gustafsson H, Scherman JB, Korreman SS, Kjær-Kristoffersen F, Hilts M, and Bäck SÅJ (2010) RapidArc treatment verification in 3D using polymer gel dosimetry and Monte Carlo simulation. Phys Med Biol 55: 4885–4898

  17. Hayashi N, Malmin RL, Watanabe Y (2014) Dosimetric verification for intensity-modulated arc therapy plans by use of 2D diode array, radiochromic film and radiosensitive polymer gel. J Radiat Res 55:541–552

    Article  CAS  Google Scholar 

  18. Olding T, Alexander KM, Jechel C, Nasr AT, Joshi C (2015) Delivery validation of VMAT stereotactic ablative body radiotherapy at commissioning. J Phys Conf Ser 573:012019

    Article  Google Scholar 

  19. Vandecasteele J, De Deene Y (2013) Evaluation of radiochromic gel dosimetry and polymer gel dosimetry in a clinical dose verification. Phys Med Biol 58:6241–6262

    Article  Google Scholar 

  20. Massillon-JL G, Minniti R, Soares CG, Maryanski MJ, Robertson S (2010) Characteristics of a new polymer gel for high-dose gradient dosimetry using a micro optical CT scanner. Appl Radiat Isot 68:144–154

    Article  CAS  Google Scholar 

  21. Low DA, Harms WB, Mutic S, Purdy JA (1998) A technique for the quantitative evaluation of dose distributions. Med Phys 25:656–661

    Article  CAS  Google Scholar 

  22. Low DA, Morele P, Chow P, Dou TH, Ju T (2013) Does the γ dose distribution comparison technique default to the distance to agreement test in clinical dose distributions. Med Phys 40:071722

    Article  Google Scholar 

  23. McAuley KB (2006) Fundamentals of polymer gel dosimeters. J Phys Conf Ser 56:35–44

Download references

Acknowledgements

This study was supported by the Ministry of Science and Technology, Executive Yuan, Taipei, Taiwan (MOST 105-2314-B-166-001-) and Changhua Christian Hospital (CTU104-CH-003).

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    Authors and Affiliations

    1. Biomaterials Translational Research Center, China Medical University Hospital, No. 91, Hsueh-Shih Road, 40402, Taichung City, Taiwan, ROC

      Chun-Hsu Yao

    2. Department of Biomedical Imaging and Radiological Science, China Medical University, No. 91, Hsueh-Shih Road, 40402, Taichung City, Taiwan, ROC

      Chun-Hsu Yao & Min-Jia Tsai

    3. School of Chinese Medicine, China Medical University, No. 91, Hsueh-Shih Road, 40402, Taichung City, Taiwan, ROC

      Chun-Hsu Yao

    4. Department of Biomedical Informatics, Asia University, 500 Lioufeng Rd., Wufeng, 41354, Taichung City, Taiwan, ROC

      Chun-Hsu Yao

    5. Department of Radiation Oncology, Changhua Christian Hospital, 135 Nanxiao St., 50006, Changhua City, Taiwan, ROC

      Tung-Hao Chang & Yuan-Chun Lai

    6. Department of Physics, National Chung Hsing University, 145 Xingda Rd., 40227, Taichung City, Taiwan, ROC

      Yuan-Chun Lai

    7. Department of Electrical Engineering, National Taipei University of Technology, No. 1, Sec. 3, Zhongxiao E. Rd., 10608, Taipei, Taiwan, ROC

      Yi-An Chen

    8. Department of Management Information Systems, Central Taiwan University of Science and Technology, No. 666, Buzih Road, Beitun District, 40601, Taichung City, Taiwan, ROC

      Yuan-Jen Chang & Chin-Hsing Chen

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    1. Chun-Hsu Yao
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    2. Tung-Hao Chang
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    Corresponding authors

    Correspondence to Yuan-Jen Chang or Chin-Hsing Chen.

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    Chun-Hsu Yao and Tung-Hao Chang have contributed equally to this work.

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    Yao, CH., Chang, TH., Tsai, MJ. et al. Dose verification of volumetric modulation arc therapy by using a NIPAM gel dosimeter combined with a parallel-beam optical computed tomography scanner. J Radioanal Nucl Chem 311, 1277–1286 (2017). https://doi.org/10.1007/s10967-016-5161-2

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    • DOI: https://doi.org/10.1007/s10967-016-5161-2

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