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Use of INAA in the homogeneity evaluation of a bovine kidney candidate reference material

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Abstract

Instrumental neutron activation analysis was used to evaluate the between bottle homogeneity and the minimum sample intake of a bovine kidney candidate reference material. The mass fractions of ten inorganic constituents were determined, obtaining satisfactory homogeneity results for all of them. Statistical analysis of the results was performed using a one way analysis of variance and multivariate techniques were applied as complementary techniques, confirming the usefulness of these techniques for homogeneity assessment.

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References

  1. Magnusson B, Örnemark U (eds) (2014) Eurachem guide: the fitness for purpose of analytical methods—a laboratory guide to method validation and related topics, 2nd edn. Available from http://www.eurachem.org. Accessed 10 May 2016

  2. Ellison SLR, King B, Rösslein M, Salit M, Williams A (eds) (2003) Eurachem/CITAC guide: traceability in chemical measurement—a guide to achieving comparable results in chemical measurement. Available from http://www.eurachem.org

  3. ISO (International Organization of Standardization) (2015) Reference materials—Good practice in using reference materials. 3rd edn. ISO Guide 33. ISO, Geneva

  4. ISO (International Organization of Standardization) (2006) Certification of reference materials. General and statistical principles, 3rd edn. ISO Guide 35. ISO, Geneva

  5. FAO (Food and Agriculture Organization of the United Nations) Food balance. http://faostat3.fao.org/browse/FB/*/E. Accessed 19 May 2016

  6. Greenberg RR, Bode P, Fernandes EAN (2011) Neutron activation analysis: a primary method of measurement. Spectrochim Acta B 66:193–241

    Article  CAS  Google Scholar 

  7. Kucera J, Soukal L (1988) Homogeneity tests and certification analyses of coal fly ash reference materials by instrumental neutron activation analysis. J Radioanal Nucl Chem 121:245–259

    Article  CAS  Google Scholar 

  8. Rossbach M, Grobecker KH (1999) Homogeneity studies of reference materials by solid sampling – AAS and INAA. Accred Qual Assur 4:498–503

    Article  CAS  Google Scholar 

  9. Moreira EG, Vasconcellos MBA, Catharino MGM, Maihara VA, Saiki M (2012) Applying INAA to the homogeneity study of a Perna perna mussel reference material. J Radioanal Nucl Chem 291:107–111

    Article  CAS  Google Scholar 

  10. Kato LS, Fernandes EAN, Bacchi MA, Elias C, Sarriés SRV, Sarriés GA, Modolo PS (2013) Instrumental neutron activation analysis for assessing homogeneity of a whole rice candidate reference material. J Radioanal Nucl Chem 297:271–275

    Article  CAS  Google Scholar 

  11. Wold S, Esbensen K, Geladi P (1987) Principal component analysis. Chemometr Intell Lab Syst 2:37–52

    Article  CAS  Google Scholar 

  12. Jolliffe IT (2002) Principal component analysis, 2nd edn. Springer, New York

    Google Scholar 

  13. Lima DC, dos Santos AMP, Araujo RGO, Scarminio IS, Bruns RE, Ferreira SLC (2010) Principal component analysis and hierarchical cluster analysis for homogeneity evaluation during the preparation of a wheat flour laboratory reference material for inorganic analysis. Microchem J 95:222–226

    Article  CAS  Google Scholar 

  14. Santos AMP, dos Santos LO, Brandao GC, Leao DJ, Bernedo AVB, Lopes RT, Lemos VA (2015) Homogeneity study of a corn flour laboratory reference material candidate for inorganic analysis. Food Chem 178:287–291

    Article  Google Scholar 

  15. Carvalho Rocha WF, Nogueira R (2011) Use of multivariate statistical analysis to evaluate experimental results for certification of two pharmaceutical reference materials. Accred Qual Assur 16:523–528

    Article  Google Scholar 

  16. Da Carvalho Rocha WF, Nogueira R, da Silva GEB, Queiroz SM, Sarmanho GF (2013) A comparison of three procedures for robust PCA of experimental results of the homogeneity test of a new sodium diclofenac candidate certified reference material. Microchem J 109:112–116

    Article  Google Scholar 

  17. ISO (International Organization of Standardization) (2015) Statistical methods for use in proficiency testing by interlaboratory comparison. 2nd edn. ISO 13528:2015. ISO, Geneva

  18. Statsoft, Inc. (2005) STATISTICA 7.0 software, Tulsa, Oklahoma, USA

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Acknowledgments

The authors would like to acknowledge the financial support of CNPQ (Brazilian National Council for Scientific and Technological Development) and EMBRAPA (Brazilian Agricultural Research Corporation) for the provision of the kidneys used to prepare the candidate reference material. The author L. Castro would like also to acknowledge the PhD fellowship from CAPES (Coordination for the Improvement of Higher Education Personnel).

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Correspondence to Liliana Castro.

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Castro, L., Moreira, E.G. & Vasconcellos, M.B.A. Use of INAA in the homogeneity evaluation of a bovine kidney candidate reference material. J Radioanal Nucl Chem 311, 1291–1298 (2017). https://doi.org/10.1007/s10967-016-4998-8

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  • DOI: https://doi.org/10.1007/s10967-016-4998-8

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