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A New Fluorescent Sensor Based on Bisindolizine Derivative

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Abstract

A fluorescent sensor based on 1,2,1ʹ,2ʹ- Tetra(methoxycarbonyl)- 3,3ʹ- bis(p-methylbenzoyl)- 7,7ʹ-bisindolizine (MBI) showing excellent selectivity towards Fe3+ ions was developed. Under optimized experimental conditions, the fluorescence intensity of 1,2,1ʹ,2ʹ- Tetramethoxycarbonyl- 3,3ʹ- bis(p-methylbenzoyl)- 7,7ʹ-bisindolizine was quenched linearly by Fe3+ ions in the range of 2.00 × 10−2 to 4.76 × 10−3 M. The limit of detection was found to be 3.17 × 10−3 M. The mechanism for quenching was investigated. The developed sensor was applied for the determination of Fe3+ in pharmaceutical samples.

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Acknowledgments

One of the authors (Sheela Gopal M) is thankful to the University Grants Commission (UGC), India, for granting FIP and Department of Applied Chemistry CUSAT, Cochin for their technical support. The author Divya Thomas express the gratitude to Council of Scientific and Industrial Research (CSIR) for the award of research fellowship.

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Authors and Affiliations

  1. Postgraduate and Research Department of Chemistry, Maharaja’s College, Ernakulam, Kerala, 682011, India

    Anitha I

  2. TMJM Govt. College, Manimalakunnu, Ernakulam, Kerala, 686662, India

    Sheela Gopal M

  3. Department of Applied Chemistry, Cochin University of Science and Technology, Kochi, 682 022, India

    Divya Thomas

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  1. Anitha I
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  2. Sheela Gopal M
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  3. Divya Thomas
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Correspondence to Anitha I.

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The authors declared that there is no conflict of interest regarding the publication of this paper.

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I, A., M, S.G. & Thomas, D. A New Fluorescent Sensor Based on Bisindolizine Derivative. J Fluoresc 26, 725–729 (2016). https://doi.org/10.1007/s10895-015-1760-5

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  • DOI: https://doi.org/10.1007/s10895-015-1760-5

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