Skip to main content
SpringerLink
Log in

Evaluating tissue oxygenation at the bedside: global, regional, or both?

  • Commentary
  • Published:
Journal of Clinical Monitoring and Computing Aims and scope Submit manuscript

Abstract

Early recognition of tissue hypoperfusion, and monitoring tissue response to resuscitation interventions, are key points in the management of critically ill patients. In the present issue of J Clin Monit Comput, Dr. Koch and coworkers present the results of a study evaluating regional and global markers of tissue perfusion in a population of septic shock patients. We propose an integrative approach to tissue perfusion assessment, where combining both, global and regional variables, might account for a better understanding of tissue oxygenation status, and might prove useful for septic shock patients' management.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  1. Koch C, Röhrig R, Monz T, Hecker A, Uhle F, Schneck E, Weigand MA, Lichtenstern C. Prospective evaluation of regional oxygen saturation to estimate central venous saturation in sepsis. J Clin Monit Comput. 2015; Mar 11.

  2. Mesquida J, Masip J, Gili G, Artigas A, Baigorri F. Thenar oxygen saturation measured by near infrared spectroscopy as a noninvasive predictor of low central venous oxygen saturation in septic patients. Intensive Care Med. 2009;35:1106–9.

    Article  PubMed  Google Scholar 

  3. Colin G, Nardi O, Polito A, Aboab J, Maxime V, Clair B, Friedman D, Orlikowski D, Sharshar T, Annane D. Masseter tissue oxygen saturation predicts normal central venous oxygen saturation during early goal-directed therapy and predicts mortality in patients with severe sepsis. Crit Care Med. 2012;40:435–40.

    Article  CAS  PubMed  Google Scholar 

  4. Podbregar M, Mozina H. Skeletal muscle oxygen saturation does not estimate mixed venous oxygen saturation in patients with severe left heart failure and additional severe sepsis or septic shock. Crit Care. 2007;11(1):R6.

    Article  PubMed Central  PubMed  Google Scholar 

  5. Lima A, van Bommel J, Jansen TC, Ince C, Bakker J. Low tissue oxygen saturation at the end of early goal-directed therapy is associated with worse outcome in critically ill patients. Crit Care. 2009;13(Suppl 5):S13.

    Article  PubMed Central  PubMed  Google Scholar 

  6. Ait-Oufella H, Joffre J, Boelle PY, Galbois A, Bourcier S, Baudel JL, Margetis D, Alves M, Offenstadt G, Guidet B, Maury E. Knee area tissue oxygen saturation is predictive of 14-day mortality in septic shock. Intensive Care Med. 2012;38:976–83.

    Article  CAS  PubMed  Google Scholar 

  7. Leone M, Blidi S, Antonini F, Meyssignac B, Bordon S, Garcin F, Charvet A, Blasco V, Albanèse J, Martin C. Oxygen tissue saturation is lower in nonsurvivors than in survivors after early resuscitation of septic shock. Anesthesiology. 2009;111:366–71.

    Article  CAS  PubMed  Google Scholar 

  8. Mesquida J, Espinal C, Gruartmoner G, Masip J, Sabatier C, Baigorri F, Pinsky MR, Artigas A. Prognostic implications of tissue oxygen saturation (StO2) in human septic shock. Intesive Care Med. 2012;38:592–7.

    Article  CAS  Google Scholar 

  9. Creteur J, Carollo T, Soldati G, Buchele G, De Backer D, Vincent JL. The prognostic value of muscle StO2 in septic patients. Intensive Care Med. 2007;33:1549–56.

    Article  PubMed  Google Scholar 

  10. Gomez H, Mesquida J, Simon P, Kim HK, Puyana JC, Ince C, Pinsky MR. Characterization of tissue oxygen saturation and the vascular occlusion test: influence of measurement sites, probe sizes and deflation thresholds. Crit Care. 2009;13(Suppl 5):S3.

    Article  PubMed Central  PubMed  Google Scholar 

  11. Mesquida J, Gruartmoner G, Espinal C. Skeletal muscle oxygen saturation (StO2) measured by near-infrared spectroscopy in the critically ill patients. Biomed Res Int. 2013;2013:502194.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  12. Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M, Early Goal-Directed Therapy Collaborative Group. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med. 2001;345(19):1368–77.

    Article  CAS  PubMed  Google Scholar 

  13. Jones AE, Shapiro NI, Trzeciak S, Emergency Medicine Shock Research Network (EMShockNet) Investigators, et al. Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: a randomized clinical trial. JAMA. 2010;303:739–46.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  14. Boulain T, Garot D, Vignon P, Lascarrou JB, Desachy A, Botoc V, Follin A, Frat JP, Bellec F, Quenot JP, Mathonnet A, Dequin PF, Clinical Research in Intensive Care and Sepsis Group. Prevalence of low central venous oxygen saturation in the first hours of intensive care unit admission and associated mortality in septic shock patients: a prospective multicentre study. Crit Care. 2014;18(6):609.

    Article  PubMed Central  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Critical Care Center, Hospital de Sabadell, Corporació Sanitària Universitària Parc Taulí, Universitat Autònoma de Barcelona,, Parc Tauli, 1, 08208, Sabadell, Spain

    Jaume Mesquida

Authors
  1. Jaume Mesquida
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jaume Mesquida.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Mesquida, J. Evaluating tissue oxygenation at the bedside: global, regional, or both?. J Clin Monit Comput 29, 431–433 (2015). https://doi.org/10.1007/s10877-015-9690-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10877-015-9690-y

Keywords

Search

Navigation